Presence of atrial natriuretic factor prohormone in
enterochromaffin cells of the human large intestine.
The prenatal development of
enterochromaffin cells in the human gastrointestinal tract.
Approximately 90% of 5-HT is synthesized by
enterochromaffin cells in the gastrointestinal tract, while most of the remaining 5-HT is produced by the neurons of the raphe nuclei in the brain.
The circulating serotonin is produced mainly in
enterochromaffin cells of the gut and excreted into the blood.
5-HT is a monoamine neurotransmitter and hormone mainly produced by
enterochromaffin cells of the gastrointestinal tract [21].
The carcinoid tumor arises from the
enterochromaffin cells of the gastrointestinal tract and can be differentiated histologically and chemically from GCT [15].
In the heart, norepinephrine is released by sympathetic nerve endings whereas serotonin is mainly produced by intestinal
enterochromaffin cells and endothelial cells.
Champaneria, "The functional characterization of normal and neoplastic human
enterochromaffin cells," The Journal of
The normal biliary tree shows very small numbers of focally distributed
enterochromaffin cells in the gallbladder neck, large bile ducts, and hepatic hilum.
Serotonin antagonists were developed through modifications in the antiemetic metoclopramide, and work by selectively blocking the serotonin receptors both centrally - in the hypothalamus, the chemoreceptor trigger zone and the cerebral cortex and peripherally in the
enterochromaffin cells of the intestinal mucosa.
In 1937, 5-HT has been found in the
enterochromaffin cells of the gastrointestinal tract, and was named enteramine because of its believed implications in the intestinal smooth muscle contraction.
Methyl syringate has been established as a specific and selective activator of TRPA1, which is expressed in sensory neurons, keratinocytes, endothelial cells,
enterochromaffin cells, and lung epithelial cells, indicating diverse roles.
