enoyl-ACP reductase

(redirected from Enoyl-acyl carrier protein reductase)
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en·o·yl-ACP re·duc·tase

(ēn'ō-il rē-dŭk'tās),
An enzyme that catalyzes hydrogenation of acyl-ACP (where ACP is acyl-carrier protein) complexes to 2,3-dehydroacyl-ACPs, with NAD+ as hydrogen acceptor; important in fatty acid metabolism.
References in periodicals archive ?
These proteins include 3-oxoacyl-acyl carrier protein synthase 2,3-oxoacyl-acyl carrier protein reductase, the acetyl-CoA carboxylase biotin carboxylase subunit, the acyl carrier protein, and NADH-dependent enoyl-acyl carrier protein reductase. Enzymes involved in fatty acid and phospholipid metabolism are most likely expressed at a higher level during the early stationary growth phase due to the reinforcement of the cell membrane that occurs during the transition of growth phases where large numbers of phospholipids are needed [53].
At bactericidal concentrations, triclosan appears to act upon multiple cell membrane and cytoplasmic targets, while at lower concentrations, triclosan affects specific targets such as the enoyl-acyl carrier protein reductase (ENR) enzyme (Yazdankhah et al., 2006).
Triclosan is known to act on enoyl-acyl carrier protein reductase, called Fab 1.