enoyl-CoA hydratase

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en·o·yl-CoA hy·dra·tase

(ēn'ō-il hī'dră-tās),
Δ2-eoyl-CoA hydratase; an enzyme catalyzing a reversible reaction between an l-3-hydroxyacyl-CoA and a 2,3- (or 3,4-) trans-enoyl-CoA in fatty acid degradation.
Synonym(s): crotonase, enoyl hydrase
References in periodicals archive ?
Primer sequences for acetyl-CoA acyltransferase (ACAA2), long-chain acyl-CoA dehydrogenase (ACADL), acyl-CoA synthetase (ACSL1), very long chain acyl-CoA dehydrogenase (ACADVL), carnitine palmitoyltransferase 1B (CPT1B), enoyl-CoA hydratase (ECH1), hydroxyacyl-CoA dehydrogenase (HADHA), pyruvate dehydrogenase kinase (PDK4), PGC-1[alpha], PGC-1[beta], PPAR[alpha], glutamate dehydrogenase, and 18S ribosomal RNA are available in Supplemental Material, Table S1 (http://dx.
isocitrate dehydrogenase and enoyl-coA hydratase were highly expressed in maslinic acid-treated Raji cells.
Indeed, maslinic acid increases energy metabolism in cells by up-regulating mitochondria isocitrate dehydrogenase and enoyl-CoA hydratase.
The second step is carried out by an enoyl-CoA hydratase, and the enzyme involved in the third step is an L 3-hydroxyacyl-CoA dehydrogenase using NAD as cofactor for the reaction, which is reduced to NADH transferring electrons to complex 1 of the respiratory chain.
In particular, the expression level of spots 26, 7, 19, 9, 6, 8 and 21, which were identified as Cathepsin H precursor, Retinal dehydrogenase 1, Enoyl-CoA hydratase, Elongation factor Tu, Ubiquinol-cytochrome-c reductase, T-complex protein 1 subunit beta and ATP synthase D chain was 9.
Both sequences were found to align with the enoyl-CoA hydratase (ECH) family of enzymes which typically catalyze the hydration of double bonded intermediates during the beta-oxidation of fatty acids.
The 3 enzymes involved are long-chain enoyl-CoA hydratase (LCEH), long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD), and long-chain 3-ketoacyl-CoA thiolase (LCTH).
Two enzymes are essential: a hydratase such as D-specific enoyl-CoA hydratase, for example, the hydratase obtained from Aeromonas caviae, and a .
LCHAD activity is associated with the [alpha]-subunit, as is the activity of longchain enoyl-CoA hydratase.