Endothelial cells


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Endothelial cells

The cells lining the inner walls of the blood vessels.
References in periodicals archive ?
The reduced expression of JAM-A on endothelial cells surface decreases FGF-2 induced angiogenesis [57] and has been correlated to an increased cleavage of IL-8 and uPAR, two angiogenic factors which are responsible for endothelial cell proliferation, extracellular matrix degradation, and the adhesion of endothelial cells to the extracellular matrix, by MMPs overexpression in fibroblast and endothelial cell [58-60].
The sources of endothelial cells utilized in investigations can be classified by the species and organs from which they have been derived.
Based on a previous work, the present study is designed to observe the effects of TWOD on the retinal vessels, hemorheology, the endothelial cells and pericytes, and the expressions of MMP-9, occludin, and claudin-5 in diabetic rats.
The study, published in the Journal of the American College of Cardiology, found that endothelial cells exposed to the e-liquids, or to blood collected from e-cigarette users shortly after vaping, are less viable and exhibit significantly increased levels of molecules implicated in DNA damage and cell death.
The researchers used human-induced pluripotent stem cells, derived endothelial cells (iPSC-ECs), and a screening approach to assess endothelial integrity following exposure to six different e-liquids with varying nicotine concentrations and blood collected from e-cigarette users.
"Until now, we had no data about how these e-liquids affect human endothelial cells. This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes.
Corneal endothelial cells are key indicators of corneal integrity and function.
Therefore, this study aimed to elucidate the levels of miR-19b in EMPs, stimulated by hypoxia, and the roles of miR-19b - wrapped within EMPs - on vascular endothelial cells.
By counting the number of sides of surrounding cells, 100 endothelial cells from each corneal area were evaluated.
The researchers found that freshly isolated endothelial cells from participants who use non-menthol- or menthol-flavored tobacco cigarettes showed impaired A23187-stimulated nitric oxide production.
Endothelium is one of the largest organ by area and consist of at least one trillion endothelial cells having more than 100 gram weight and covering more than 3000 square meters area in an adult human body.

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