The reduced expression of JAM-A on endothelial cells
surface decreases FGF-2 induced angiogenesis  and has been correlated to an increased cleavage of IL-8 and uPAR, two angiogenic factors which are responsible for endothelial cell
proliferation, extracellular matrix degradation, and the adhesion of endothelial cells
to the extracellular matrix, by MMPs overexpression in fibroblast and endothelial cell
The sources of endothelial cells
utilized in investigations can be classified by the species and organs from which they have been derived.
Based on a previous work, the present study is designed to observe the effects of TWOD on the retinal vessels, hemorheology, the endothelial cells
and pericytes, and the expressions of MMP-9, occludin, and claudin-5 in diabetic rats.
The study, published in the Journal of the American College of Cardiology, found that endothelial cells
exposed to the e-liquids, or to blood collected from e-cigarette users shortly after vaping, are less viable and exhibit significantly increased levels of molecules implicated in DNA damage and cell death.
The researchers used human-induced pluripotent stem cells, derived endothelial cells
(iPSC-ECs), and a screening approach to assess endothelial integrity following exposure to six different e-liquids with varying nicotine concentrations and blood collected from e-cigarette users.
AQP-1 immunoreactivity is detected on sinusoidal endothelial cells
and microvascular endothelial cells
in the portal tract (Fig.
"Until now, we had no data about how these e-liquids affect human endothelial cells
. This study clearly shows that e-cigarettes are not a safe alternative to traditional cigarettes.
Corneal endothelial cells
are key indicators of corneal integrity and function.
Therefore, this study aimed to elucidate the levels of miR-19b in EMPs, stimulated by hypoxia, and the roles of miR-19b - wrapped within EMPs - on vascular endothelial cells
By counting the number of sides of surrounding cells, 100 endothelial cells
from each corneal area were evaluated.
The researchers found that freshly isolated endothelial cells
from participants who use non-menthol- or menthol-flavored tobacco cigarettes showed impaired A23187-stimulated nitric oxide production.
Endothelium is one of the largest organ by area and consist of at least one trillion endothelial cells
having more than 100 gram weight and covering more than 3000 square meters area in an adult human body.