endoglin


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en·do·glin

(en'dō-glin), [MIM*131195]
A protein on the surface of endothelial cells that binds to transforming growth factor-β.

en·do·glin

(en'dō-glin)
A protein on the surface of endothelial cells that binds to transforming growth factor-β.

endoglin

An antiangiogenic protein. A rise in the circulating level of soluble endoglin heralds the onset of PRE-ECLAMPSIA within two to three months.
References in periodicals archive ?
Soluble endoglin contributes to the pathogenesis of preeclampsia.
Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.
Upon commercialization of Endoglin products by Alere, Miraculins will receive ongoing royalties on sales subject to terms set out in the license agreement.
A few years prior to Tim's visit to the authors' pediatric HHT center, Tim's father had genetic testing that revealed the endoglin mutation or HHT1.
Use of preoperative plasma endoglin for prediction of lymph node metastasis in patients with clinically localized prostate cancer.
Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants.
30) Increasing evidence suggest that endoglin (CD105) is a new powerful marker of neovascularization in solid malignancies (31) and positive CD105 vessels in Adenoid cystic carcinomas increases risk of metastasis.
Vascular endothelial growth factor and endoglin (CD-105) in gastric cancer.
Angiotensin II via activation of type 1 receptor upregulates expression of endoglin in human coronary artery endothelial cells.
Pregnant women with too much of a protein called soluble endoglin in their blood have a heightened risk of preeclampsia, the researchers say.
University of Utah (Salt Lake City, UT) has patented transgenic mice genetically engineered for a deficiency in endoglin production.