associated with type 2 diabetes mellitus and pancreatic cancer are distinct, the former represented by an increase in glucagon and the latter characterized by a reduction in islet size," said Sajan Nagpal, MD, of the Mayo Clinic in Rochester, Minn., at Digestive Disease Week 2018.
Glucocrinology includes in its ambit, endocrinopathies
that may cause secondary diabetes, coexist with metabolic syndrome, precipitate hypoglycaemia, lead to refractory hyperglycaemia, or simply coexist with diabetes.
(4) The cellular damage caused by iron overload in patients with TDT leads to complications such as endocrinopathies
, cardiac failure, and hepatic iron overload with subsequent cirrhosis.
Other manifestations of Carney's syndrome include cutaneous myxomas, hyperpigmentation of the skin, and endocrinopathies
Erythema dyschromicum perstans has been reported in association with exposure to drugs (penicillin, benzodiazepines, ethambutol, fluoxetine, and omeprazole), radiographic contrast media (barium sulfate), parasitic infestations (whipworm), fungicide (chlorothalonil), chemicals (ammonium nitrate), herbal consumption (Tokishakuyakusa), endocrinopathies
(hypothyroidism, diabetes mellitus), dyslipidemia, infections (human immunodeficiency virus, hepatitis C, and enterovirus), and cobalt allergy [16-20].
Commonly described irAEs include rash, pruritus, colitis, hepatitis, and various endocrinopathies
, such as thyroiditis and hypophysitis .
(5) Other theories include a cutaneous response to underlying endocrinopathies
, ultraviolet light, and localized amyloidosis.
One of the most common endocrinopathies
in women of childbearing age, PCOS has a prevalence of 4% to 12% in American women (Lucidi, 2016).
(2012), suggesting that increased serum ferritin levels was related to the endocrinopathies
involving various endocrine structures like pancreas, interior pituitary, thyroid, parathyroid and adrenal glands.
All five checkpoint inhibitor-treated groups might have pneumonitis, hepatitis, colitis, and endocrinopathies
(e.g., thyroid disease, adrenal insufficiency, hypophysitis, and type 1 diabetes).
Diabetes mellitus and thyroid diseases represent two of the most common endocrinopathies
Polyostotic forms, characterized by the involvement of more than one bone, include three different types: (1) craniofacial fibrous dysplasia, in which the maxilla and adjacent bones are involved; (2) Jaffe's type (or Jaffe-Lichtenstein type), in which there is multiple bone involvement along with an irregular macular melanin pigmentation of the skin (cafe-au-lait spots); and rarely (McCune-Albright syndrome or Albright's syndrome, MAS), in which there is progressive bone involvement, at least one of the typical hyperfunctioning endocrinopathies
and/or cafee-au-lait spots, with almost any combination possible.