Emedastine difumarate Ophthalmology A topical agent for temporary relief of allergic conjunctivitis
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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The four ophthalmic agents in this class are alcaftadine (Lastacaft), azelastine (Optivar), emedastine (Emadine), and epinastine (Elestat).
Topical ocular antihistamine-decongestants such as levocabastine and emadine can block histamine action at the [H.sub.1]- and [H.sub.2]-receptors in the conjunctiva, but do not slow the constant release of histamine from conjunctival mast cells.