Proteus syndrome

(redirected from Elephant man in context of NF)
Also found in: Dictionary.
Related to Elephant man in context of NF: elephant man's disease

Pro·te·us syn·drome

[MIM*176920]
a sporadic disorder of possible genetic origin, having a variable and changing phenotype; characterized by gigantism of the hands and feet, by distorted, abnormal growth, pigmented nevi, thickening of the palms and soles, vascular malformations, and subcutaneous lipomas; often confused with neurofibromatosis type I.
Synonym(s): elephant man's disease (1)
[G. Proteus, a sea god who had the power to change his form]
A rare autosomal dominant [MIM 176920] condition characterised by acral gigantism, plantar hyperplasia, hemangiomas, lipomas, varicosities, linear verrucae, nevi, macrocephaly, cranial hyperostosis, pachydermy, and hypertrophy of long bones

Pro·te·us syn·drome

(prō'tē-ŭs sin'drōm)
A sporadic disorder of possible genetic origin, having a variable and changing phenotype characterized by gigantism of the hands and feet, distorted abnormal growth, pigmented nevi, thickening of the palms and soles, vascular malformations, and subcutaneous lipomas; often confused with neurofibromatosis type II.
Synonym(s): elephant man disease (1) .
[G. Proteus, a sea god who had the power to change his form]