electroporation

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e·lec·tro·por·a·tion

(ē-lek'trō-pōr-ā'shŭn),
A technique in which a brief electric shock is applied to cells; momentary holes open briefly in the plasma membrane, allowing the entry of macromolecules (for example, a way of introducing new DNA into a cell).
Farlex Partner Medical Dictionary © Farlex 2012

electroporation

(ĭ-lĕk′trō-pə-rā′shən)
n.
A process of applying a high-voltage electrical pulse to a living cell, causing temporary permeability of the cell membrane, through which a foreign material such as DNA may pass.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

electroporation

a method in which CELLS are subjected to an electrical impulse that leads to the temporary formation of pores in the cell MEMBRANE. Such pores enable commodities such as DNA, PROTEINS and ATP to pass into the cell, before the pores are repaired. Electroporation provides a means of transforming cells (see TRANSFORMATION). It can also be used to deliver DRUGS across the skin and to transfer GENETIC MATERIAL to targetted cells, in GENE THERAPY.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
With the exception of the cost for an electroporator machine, the electroporation method is advantageous because of large scale transfection and no need for a transfection reagent.
The electroporator (BioRad) was set to 2.5 kV, 25 [micro]F and the pulse controller to 200 omega.
In this work we present a flexible microsecond electroporator optimization using PSPICE model of the device, which can be used to estimate the influence of transient processes during pulse generation and allows design and implementation of the compensation circuit for parasitic load handling and damping.
The electroporator NEPA21 (NEPA GENE, Chiba, Japan) was used for introducing plasmids into hiPS cells [19].
- Trial Size Ingenio[R] Electroporation Kits for all conventional electroporators, such as Bio-Rad[R] and Harvard-BTX[R] (0.4 cm cuvettes and cell droppers)