electrochemiluminescence


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electrochemiluminescence

, electrochemoluminescence (ē-lek″trō-kēm″ĭ-loo″mĭ-nes′ĕns) (ē-lek″trō-kēm″ō-loo″mĭ-nes′ĕns)
The production of visible light by an electrochemical reaction in which molecules, after becoming electronically excited, release visible electromagnetic energy when they return to their relaxed state. Electrochemiluminescence is used in laboratory science as a means of measuring the concentration of specific chemicals in solution. Light-emitting molecules that commonly bind to the chemical of interest are introduced into the solution, and the amount of light given off by the “labeled” or “tagged” chemical is measured.
References in periodicals archive ?
Electrochemiluminescence (ECL), or electrogenerated chemiluminescence, is the process in which reactants are generated during the high-energy electron-transfer reactions occurring at the surface of the working electrodes without the need of an external light source [5].
(13.) Nishimura J, Arai N, Fujimatsu J (2007) Measurement of serum undercarboxylated osteocalcin by electrochemiluminescence immunoassay with "Picolumi ucOC" kit.
Hu et al., "Electrochemiluminescence biosensor for folate receptor based on terminal protection of small-molecule-linked DNA," Biosensors and Bioelectronics, vol.
Chi, "Immobilizing water-soluble graphene quantum dots with gold nanoparticles for a low potential electrochemiluminescence immunosensor," Nanoscale, vol.
Zhang et al., "Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk," Diabetes Technology & Therapeutics, vol.
AUC: Area under the curve BALF: Bronchoalveolar lavage fluid BP: Bacterial pneumonia CCL18: CC-chemokine ligand 18 [D.sub.LCO]: Diffusing capacity of the lung for carbon monoxide ECLIA: Electrochemiluminescence immunoassay ELISA: Enzyme-linked immunosorbent assay [FEV.sub.1]: Forced expiratory volume in 1 second HC: Healthy controls HP: Hypersensitivity pneumonia HR: Hazard ratio HRCT: High-resolution computed tomography ILDs: Interstitial lung diseases IPF: Idiopathic pulmonary fibrosis KL-6: Krebs von den Lungen-6 MMP-7: Matrix metalloproteinase-7 NSIP: Nonspecific interstitial pneumonia ROC: Receiver operating characteristic SP-A: Surfactant protein-A SP-D: Surfactant protein-D VC: Vital capacity.
Hypothyroidism was defined as serum thyroid-stimulating hormone (TSH) level greater than 4.2 mlU/l (reference; 0.27-4.2 mlU/l, electrochemiluminescence immunoassay, COBAS INTEGRA 400 PLUS, Roche Diagnostics).
Antithyroid antibodies were evaluated to determine Graves' disease by electrochemiluminescence immunoassay method using the Cobas e601 analyzer (Roche Diagnostics; Indianapolis, Indiana) [11].
Lacking historical information about the reference drug's assay format as well as platform and reagents used in its development, we selected an electrochemiluminescence base (ECL) format using the Meso Scale Discovery (MSD) platform for both the PK and ADA assay formats as this technique offers a large dynamic range.
Serum TSH, T4, and T3 levels were estimated using Cobas e411, which is based on electrochemiluminescence (ECL) technology.
Vitamin D testing at VPS Healthcare laboratories is performed using electrochemiluminescence (ECL) detection technology, which is approved by FDA (US Food and Drug Administration) offering broad measuring range and high detection for assessment of patients.

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