edible vaccine


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A vaccine in which an antigenic protein is engineered into an edible plant; after ingestion, the protein is uncloaked and recognized by the immune system

edible vaccine

A genetically manipulated food containing organisms or related antigens that may provide active immunity against infection. Edible vaccines against many microorganisms are being developed, with the goal of using them to vaccinate children in nonindustrialized countries where there are obstacles to the use of traditional injectable vaccines.
See also: vaccine
References in periodicals archive ?
Clinical trials led by Nobel Prize winner Dr Barry Marshall have identified certain strains of stomach bacteria, which are safe to use in humans as the basis for edible vaccines.
The researchers also detected antibodies in the feces of six of the people who had received the edible vaccine. That indicates that the immune agents were so plentiful in the gut that some were being excreted, and that's a good sign, says study coauthor Charles J.
Plant based edible vaccines: new frontiers for animal disease prophylaxis.
Biotech corporations have expanded on their scientific experiments with our fund by creating edible vaccines and pharmaceutical crops, Over 400 genetically altered "functional foods" are in development by twenty biotech corporations from around the world.
Current efforts in the vaccine manufacturing field include product research and development pertaining to injectable combination vaccines and to non-injectable vaccines, including those administered via inhalation and even edible vaccines.
A plant has been genetically modified to carry a vaccine to fight measles, offering the prospect of edible vaccines. The technique may also be applied to protecting a range of viral diseases, including HIV and malaria, according to a team of scientists at Monash University in Australia.
The NRC report suggests that edible vaccines, which are currently being developed, could also be used by soldiers in the field to fend off common ailments or diarrhea caused by intestinal viruses.
GMO plants with specific consumer benefits that are in the pipeline include: 1) plants containing edible vaccines (e.g., a hepatitis vaccine in potatoes); 2) GMO plants with increased vitamins and proteins for improved health; and 3) hypoallergenic plants, including foods such as milk, wheat and peanuts.
Current development is focused not only on high-value therapeutic proteins, edible vaccines, antibodies for human immunotherapy, but also on industrial applications like production of enzymes for food and feed additives, engineering plants in order to produce specially designed seed which can be used as a delivery vehicle for industrial enzymes [3-18].
"The winged bean collection has been important in our preliminary studies, which we hope will allow us to design edible vaccines in the future."
In January of 1996, a patent for the process, product and transgenicplant issued to Edible Vaccines, Inc.
Kalorama estimates that needle-free drug delivery methods--which include patches, edible vaccines, pen injectors and more--will likely see a significant increase in revenues, with annual growth averaging 15.1% from 2011 through 2016 to reach $6.2 billion.