endocrine disruptor

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endocrine disruptor

A substance which interferes with the synthesis, secretion, transport, binding, action or elimination of natural hormones in the body that are responsible for development, behaviour, fertility and maintenance of homeostasis (normal cell metabolism).

Examples
DDT, polychlorinated biphenyls, bisphenol A, polybrominated diphenyl ethers, phthalates.

endocrine disruptor

(dĭs-rŭp′tĕr)
A chemical that may imitate or block the function of natural hormones if it is absorbed by the body. Many pesticides and plasticizing compounds, e.g., phthalates, are thought to disrupt endocrine pathways, esp. if they are absorbed by pregnant women during embryonic and fetal development.
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References in periodicals archive ?
Why is it important in evaluating the effect of EDCs on the HPT axis?
In many of these countries, agriculture is the largest economic sector and the most significant user of manufactured chemicals, many of which are EDCs (Gore et al.
To measure EDC exposure, the participants had their urine analysed
Of particular concern is the proposal that EDCs must have a single known "mode of action," which "represents a fundamental misunderstanding of how endocrine signaling works by connecting different organ systems within the body," said Dr.
2014), may indicate that many of the fish that we collected in our samples were suffering from other physiological impairments that could be associated with EDCs (Jobling and Tyler, 2003b).
Exogenous Administration of NaHS Lowered Blood Pressure and Ameliorated EDCs in Renal Artery in Hypertensive Rats.
The idea of EDC is to restrict data entry: to be invalid (if possible), to avoid trivial data capture, to be readable (since it's recorded on the computer), and to have more complex rules that allow you to compare data across case report forms," said Keet.
The annual award, sponsored by Sodexo Canada, recognizes an outstanding EDC, affirming the value EDCs bring to Aboriginal communities through employment, business development and revenue generation.
There are many other suspected EDCs, mostly pesticides and plasticizers (such as phthalate esters used in PVCs to increase flexibility), but also additives or contaminants in food and personal care products.
Energo-PRO, Austrian-based EVN and CEZ Razprelenie Bulgaria AD, a subsidiary of CEZ group where the Czech Republic is a majority shareholder, are the EDCs operating in Bulgaria.