ectopic expression


Also found in: Encyclopedia, Wikipedia.

ectopic expression

The expression of a gene in a tissue in which it is not normally expressed. This occurs only in artificial situations such as in transgenic animals.
References in periodicals archive ?
As a result, CCK-8 assay and colony formation assay showed that ectopic expression of HtrA1 significantly suppressed the growth ability and colony number of PANC-1 cells (Figure 2C and D).
(3) However, to have better understanding of this ectopic expression, much more research is needed concerning [beta] hCG molecular structure and in particular the forms expressed by cancer.
Although the biological functions of this gene are not clear, ectopic expression of this transcription factor can help to understand the functional activity of this gene in the proliferation and maintenance of stem cell activity of cancer cells.
Phenotypic nonspecificity is observed for HD containing TFs in the induction of wingless, eyeless, arista to tarsus transformations, ectopic thoracic beards, Hox-mediated control of autophagy, suppression of spalt expression phenotypes following ectopic expression and the rescue of neuromere development and mesoderm formation.
For ectopic expression of GBP1, lentiviruses expressing human GBP1 gene were purchased from Fulengen Inc.
Ectopic expression of miR-152 indirectly induced expression of SFRP4, a negative regulator of the Wnt pathway, by targeting DNMT1 [23].
Figure 1(a) shows that ectopic expression of synthetic pre-miR-128 slightly decreases the luciferase activity of the construct harboring the 3UTR region (wt) of Nrf2 in HEK293 cells.
To investigate functions of miR-31 in gastric cancer cell proliferation, we utilized ectopic expression of miR-31 and measured cell growth of two gastric cancer cell lines BGC-823 and SGC-7901 using CCK-8 method.
Ectopic expression of rice OsNCED3 in Arabidopsis increases ABA level and alters leaf morphology.
This study has led to the identification of a novel factor, whose ectopic expression converts mouse liver cells into pancreatic cells.