Compound Docking scores (kcal x [mol.sup.-1]) Trichlorfon -5.7 Echothiophate
-5.9 Isoflurophate -5.9 Pyridostigmine -6.3 Neostigmine -7.5 Parathion -7.6 Rivastigmine -7.9 Tacrine -8.8 Ladostigil -9.1 Physostigmine -9.1 Huperzine A -9.7 Ungeremine -10 Galantamine -10.2 Donepezil -12.1 2 -9.1 3 -9.4 6 -7.8 7 -5.7 8 -7.6 9 -7.9 14 -10
iodide treatment of glaucoma in pregnancy.
Topical application of 0.03% echothiophate
iodide or 0.025% Isoflurophate (both organophosphates) has been successful for T.
Examples of organophosphates include insecticides (Malathion, parathion, diazinon, fenthion, dichlorvos, chlorpyrifos, ethion), nerve gases (Soman, sarin, tabun, VX), ophthalmic agents (Echothiophate
, isoflurophate), and anthelmintics (Trichlorfon).
iodide (Phospholine Iodide), there is one case report of a normal full-term infant whose mother was treated with the agent up to 32 weeks' gestation and then with pilocarpine for 8 weeks (Arch Ophthalmol.
In the present study, we evaluated this possibility by measuring light emission upon stimulation with KCI or veratridine of synaptosomes pretreated with 47 [micro]mol [1.sup.-1] of echothiophate
iodide, an acetylcholinesterase inhibitor.
* Subjects who are on myotics like carbachol, demecarium, echothiophate
, isoflurophate, neostigmine and physiostigmine.