East African sleeping sickness


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Rho·de·sian try·pan·o·so·mi·a·sis

a disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anemic, and frequently die from cardiac failure.
References in periodicals archive ?
For the treatment of East African sleeping sickness, only suramin and melarsoprol are used in the first and second stage of the disease, respectively.
In the present report the use of PCR is illustrated in a recently encountered case of East African sleeping sickness. This case suggests that suramin toxicity may be an effect of trypanosomal decay rather than the result of direct toxicity.
It might work against the T bruce/ variation that causes the more virulent East African sleeping sickness and might also kill the parasite responsible for Chagas disease, Trypanosoma cruzi, Olson says.--N.S.

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