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114) EUS-FNA has also been used for assessing biliary lesions; however, there is concern for needle track seeding, especially in proximal bile duct lesions.
Moreover, the results may be helpful in current clinical settings involving EUS-FNA assessment.
Results: At the end of EUS-FNA, 5 patients had been diagnosed with malignancy (two small cell lung cancer and three non-small cell lung cancer) and 4 had been diagnosed with benign disease (two pulmonary tuberculosis, one benign mediastinal cystic lesion and one reactive lymph node).
EUS-FNA biopsy is a safe and effective technique for diagnosing and staging PDAC; however, measurement of RNA production can be problematic because of the poor quality of the RNA extracted from these biopsies [(24) and our own experience].
Figure 3 illustrates an example of an EUS-FNA of a metastatic melanoma in the pancreatic body.
Conclusion: Infectious complications among patients undergoing EUS-FNA appear to be similar between those receiving prophylactic antibiotics and those who do not.
To define the ability of real-time RT-PCR to detect metastatic NSCLC in MLNs, we procured by EUS-FNA nine MLNs containing metastatic NSCLC (five adenocarcinomas, one large cell carcinoma, one squamous cell carcinoma, and two uncharacterized carcinomas).
7-9) However, going forward, with the increasing utilization of EUS-FNA, the latter problem can ameliorated by requesting additional passes at the time of rapid on-site adequacy assessment.
In order to meet the burgeoning field of personalized care in pancreatic diseases, (13) there will likely need to be a shift in the paradigm on intent of EUS-FNA.
Since EUS-FNA can be used to obtain tissue and is generally felt to have fewer complications, such as pancreatitis and peritonitis, than large-core needle biopsies and wedge biopsies of the pancreas, this modality has gained increased use.