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To identify the pertinent references, a PubMed search using the terms next-generation sequencing, pancreas, pancreatic lesions, pancreatic tumors, and EUS-FNA was performed covering the years 2000-2017.
Although EUS-FNA is considered as the gold standard for the diagnosis of malignant LNs, with PPV and specificity approaching 100%, FNA needs appropriate training and good experience and may be associated with many complications [8].
Layfield, "A comparative needle study: EUS-FNA procedures using the HD ProCore[TM] and EchoTip[R] 22-gauge needle types," Diagnostic Cytopathology, vol.
Our outcomes were the diagnostic yields of C-TBNA, EBUS-TBNA, and EUS-FNA, diagnostic yield as a function of LN station, diagnostic yield as a function of LN size, the percentage of cases where additional ultrasonographic procedures were required after C-TBNA, average number of cells per LN aspirate, and proportion of samples with sufficient cells to perform ancillary studies if needed.
Wallace, "EUS-FNA and biomarkers for the staging of non-small cell lung cancer," Endoscopy, vol.
Pancreatic lipoma diagnosed using EUS-FNA. A case report.
(8,21-24) In a study of 233 patients performed at our institution, EUS-FNA had a specificity of 100%, but the sensitivity was only 91% because of sampling error.
Various endoscopic tissue acquisition methods, including the endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), endoscopic ultrasound-guided trucut biopsy, cold forceps or jumbo forceps bite-on-bite biopsies, unroofing techniques, endoscopic submucosal resection or dissection, and submucosal tunneling, have been used for cytohistopathological diagnosis (8).