MAPK3

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MAPK3

A gene on chromosome 16p11.2 that encodes a protein of the MAP kinase family. MAP kinases (e.g., extracellular signal-regulated kinases) integrate multiple biochemical signals and are involved in cell proliferation, differentiation, transcription, regulation and development. Once MAPK3 is activated by phosphorylation by an upstream kinase, it translocates to the nucleus of the stimulated cell, where it phosphorylates target molecules.
References in periodicals archive ?
A variant of Cas9 with nuclease activity modulated by the presence of the tamoxifen analogue 4-HT (Figure 3(d)) [58] was based on fusions of human estrogen receptor 2 (ERT2) domain at either the N- or C-terminus of Cas9, in which the positions of the nuclear localization signal (NLS) was varied.
In terms of shares, on average, each broadcast TV network took the following percentages: ANT 1, 16.35; ALPHA, 14.1; SKAI, 13.26; STAR, 10.78; MEGA, 8.98; EPSILON, 7.61; ERTi, 5.14; ERT2, 2.66 and MAK TV, 0.84.
Programs audience measurement and registration services of three television stations (ert1 - ert2 - ert3) and panhellenic all television stations and / or regional scope and the recording of tv behavior of viewers on a nationwide basis for a period of 1 year.