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A gene on chromosome 7q32-q36 that encodes a member of the ephrin-A receptor subfamily of receptor tyrosine kinases, which promiscuously bind membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. It induces cell attachment to the extracellular matrix, inhibiting cell spreading and motility by regulating ILK and downstream RHOA and RAC. EPHA1 also plays a role in angiogenesis and cell proliferation, and may play a role in apoptosis. It is overexpressed in certain carcinomas.
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Patient discussion about EPH

Q. after a pedicure, the soles of my feet are dark w/freckles, skin is itchy/thick, my derm says its eczema,help! the pedicure was in fall, 2002. I mad a mistake and wore nylon boots during a storm, the dye never fully disappeared. I would scrub the soles of my feet until I couldn't walk. However, within the last 4 months both heels are itchy, thick, dark-er and now they both have dark legions/ freckles have formed.

A. Are you sure you are going to a clean sterile saloon? It is very important to make sure they use sterile tools for a pedicure because they can transfer fungal infections very easily. Either way you should see a dermatologist to get the right kind of cream treatment for your feet.

More discussions about EPH
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References in periodicals archive ?
A broadened scope for environmental health could 1) create BEs with fewer acute health hazards, decreasing the need for conventional health protection, 2) impact a wider range of population-wide behaviours needed to prevent and control the current chronic disease epidemics, thus realizing multiple health benefits with modest resource additions, and 3) increase access to resources for EPH through collaboration.
In a situation of massive PPH the obstetrician is faced with dilemma of a conservative compared with aggressive management approach, this choice should weigh the woman's desire for future fertility compared with the risk that further delay in EPH may lead to severe morbidity and maternal death.
But God allowed Claude to survive the crisis and grow up to be an active and creative adult, for which Eph and I cannot thank Him enough.
Eph family of receptors are interesting targets for molecular cancer therapy since they are mostly overexpressed in tumors and seem to be involved in tumor cell survival and proliferation, invasion, metastasis, and angiogenesis.
[8] In developed countries, the reported incidence of EPH is below 0.1% of the normal deliveries performed, while in developing countries the incidence rates are high as 1-5/1,000 deliveries performed.
* EPH involvement is not limited only to domains where EPH documentation will be submitted.
The total area of the EPH was 12 m (W)x20 m (L), with the internal stalls having a dimension of 2.1 mx5.6 m as specified by MWPS 32 (1988).
All the EPH systems produce results that express quantitation of fraction percentage to the tenths decimal.
The Anorak says: Doug and Eph Smith went through the six-race card at Kempton on April 23, 1962.
I believe Catholic Insight and RPC have a lot in common--"one Lord, one faith" (Eph. 4:5).
The unit will produce Dowanol EPh and PPh and will be designed to meet immediate and forecast demand for these solvents.
Eph receptor tyrosine kinases and their ligands, the ephrins, are involved in a variety of biological processes, including normal embryonic development, cell adhesion, cell migration, tissue morphogenesis, angiogenesis and cancer.