CXCL5

(redirected from ENA-78)
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CXCL5

A gene on chromosome 4q13.3 that encodes an inflammatory chemokine, which is involved in neutrophil activation and co-produced with IL-8 in response to stimulation by either IL-1 or tumour necrosis factor-alpha (TNF-alpha).
References in periodicals archive ?
Zimmerman, "Human Endothelial Cells Synthesize ENA-78: relationship to IL-8 and to Signaling of PMN Adhesion," The American Journal of Respiratory Cell and Molecular Biology, vol.
Walz, "Neutrophil-activating protein ENA-78 and IL-8 exhibit different patterns of expression in lipopolysaccharide- and cytokine-stimulated human monocytes," The Journal of Immunology, vol.
Philippova et al., "Bronchial Smooth Muscle Cells of Asthmatics Promote Angiogenesis through Elevated Secretion of CXC-Chemokines (ENA-78, GRO-[alpha], and IL-8)," PLoS ONE, vol.
The study showed that the mRNA expression of the chemokines ENA-78 and RANTES, as well as the inflammatory cytokines TNF[alpha] and IL-6, was significantly increased in the ectopic lesion compared to those in the matched eutopic tissue in women with endometriosis.
In this study we found a significant increase in the expression of RANTES and ENA-78 in the RVS lesions compared to the matching eutopic tissue.
Mueller, "Basal and cytokine-stimulated production of epithelial neutrophil activating peptide-78 (ENA-78) and interleukin-8 (IL8) by cultured human endometrial epithelial and stromal cells," Fertility and Sterility, vol.