ELP3

A gene on chromosome 8p21.1 that encodes a catalytic histone acetyltransferase subunit of the RNA polymerase-II elongator complex, a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme involved in transcriptional elongation. ELP3 may also have methyltransferase activity.

References in periodicals archive ?

The members of GNAT family include Gcn5 and its distantly related proteins Hap2 and Elp3 among which Gcn5 is the most studied one.

Targeting protein acetylation for improving cancer therapy

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