ELF2


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Related to ELF2: ELF4

ELF2

A gene on chromosome 4q28 that encodes a ubiquitously expressed protein, the activity of which is isoform dependent: 
• Isoform 1 activates LYN and BLK promoters, and acts synergistically with RUNX1 to transactivate the BLK promoter;
• Isoform 2 may repress RUNX1-mediated transactivation.
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References in periodicals archive ?
Fold Gene Description change elF2 signaling E1F1AX Eukaryotic translation initiation factor 1A, -1.343 X-Linked EIF2B3 Eukaryotic translation initiation factor 2B, -1.361 subunit 3 gamma, 58kDa EIF3B Eukaryotic translation initiation factor 3, -1.385 subunit B EIF4G1 Eukaryotic translation initiation factor 4 -1.306 gamma, 1 MAP2K1 Mitogen-activated protein kinase inase 1 1.306 PPP1R15A Protein phosphatase 1, regulatory subunit 15A 1.784 RPL7L1 Ribosomal protein L7-like 1 -1.283 RPL14 Ribosomal protein L14 -1.297 RPL36 Ribosomal protein L36 -1.424 RPL36A Ribosomal protein L36a -1.400 RPS2 Ribosomal protein S2 -1.376 RPS7 Ribosomal protein S7 -1.619 RPS15 Ribosomal protein S15 -1.641 Table 4 Molecular docking of CPT to P13K (PDB ID: 1E8Y) and eIF4A (PDB ID:2G9N).
(The mean difference in blood lead levels within each low, medium, and high contamination category for ELF1 = 0.7, 1.9, 3.2 [micro]g/dL, and for ELF2 = 1.7, 0.8, and 2.9 [micro]g/dL, respectively.) The results for both environmental factors are similar.