CACNB4

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CACNB4

A gene on chromosome 2q22-q23 that encodes a beta subunit of a voltage-dependent calcium channel, which plays a regulatory role in calcium channel function by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling alpha-1 subunit membrane targeting.

Molecular pathology
CACNB4 mutations have been associated with idiopathic generalised epilepsy and juvenile myoclonic epilepsy.
References in periodicals archive ?
EJM is now a wholly owned subsidiary of TranSmart, and both companies will retain their respective names at this time.
Weng L, Temminghoff EJM, van Riemsdijk WH (2001) Contribution of individual sorbents to the control of heavy metal activity in sandy soil.
EJM boasts a diversified fleet of light mid-sized jets based all over the nation.
Besides illustrating the multi-racial nature of the environmental justice movement (EJM), the case studies provide the raw material through which the authors theorize the EJM.
Among the many works premiered at the biennial, the most important was Belgian choreographer Frederic Flamand's dual ballet EJM 1 -- EJM 2, which featured the combined forces of his own Charleroi/Danses -- Plan K and the Lyons National Opera Ballet.
has leased an 86,970-square-foot building in the Valencia Commerce Center from EJM Development of West Hollywood, officials said Wednesday.
In the world of marketing ideas, as often depicted in the erudite pages of the EJM, it is said that marketing management has, among other things, to do with the behaviour of people in organizations of various kinds.
Exhibit 1, below, illustrates this for EJM Savings institution.
company, EJM has leveraged the world's largest private aviation infrastructure to bring Support Services clients important cost savings on critical operational elements including fuel, aircraft brokerage, maintenance, as well as crew recruiting and training.
Dentons, the world's leading global law firm, today announced an affiliation with EJM Associates to provide strategic advice to clients on a range of energy policy, innovation and security issues.
Shime J, Mocarski EJM, Hastings D, Webb GD, Mclaughlin PR.
New Construction: 51 Astor Place, Owner/management firm: EJM Equities, Inc.