EIF1AY

EIF1AY

A gene on chromosome Yq11.223 that encodes a ubiquitous translation initiation factor required for the maximum rate of protein biosynthesis. It enhances ribosome dissociation into subunits and stabilises the binding of the initiator Met-tRNA(I) to 40S ribosomal subunits.
References in periodicals archive ?
Moreover, CAV1, CD200R1, HRASLS2, MIA, TNFRSF17, CXCR3, and AQP3 among the top twenty upregulated genes as well as EIF1AY, DDX3Y UTY, IL7R, and CD3D among the top twenty downregulated genes are involved in immune function of organism.
Moreover, CAV1, CD200R1, HRASLS2, MIA, TNFRSF17, CXCR3, AQP3, CCR9, IFNAR1, and CEACAM1 among the top twenty upregulated genes as well as EIF1AY, DDX3Y UTY, IL7R, IGFBP7, and GNLY among the top twenty downregulated genes are involved in immune function of organism, while other genes function in immune responses was not clearly identified.
Moreover, CAV1, CD200R1, HRASLS2, MIA, TNFRSF17, CXCR3, and AQP3 among the top twenty upregulated genes as well as EIF1AY, DDX3Y UT Y, IL7R and CD3D among the top twenty downregulated genes are involved in immune function of organism, while other genes function in immune responses was not clearly identified.
The genes (EIF1AY and DDX3Y) are located on the nonrecombining region of the human Y chromosome and were identified to be associate with immunology, RNA metabolism, vesicle fusion, and angiogenesis [52].
Two candidates, representing genes RPS4Y1 (ribosomal protein S4, Y-linked 1) and EIF1AY (eukaryotic translation initiation factor 1A, Y-linked), were detected with reliable signals in all male samples, whereas transcripts for these 2 genes were undetected in all but one female sample.