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Moreover, numerous studies identified several other target genes of miR-210, including Efna3 , neuronal pentraxin 1 , E2f3 , PTPN2 , and ptplb , suggesting that miR-210 has diverse roles in angiogenesis, DNA repair, cell cycle, migration, and apoptosis.
MiR-210 also promotes cardiac cell survival by blocking expression of the negative regulators of VEGF signaling (Efna3 and Ptp1b) and apoptosis inducing factor-mitochondrion associated 3 (AIFM3) [81, 82].
or EFNA3. [Y.sub.it - 1] and [EF.sub.it - 1] are the initial values for the relevant income and freedom scores of interest, respectively, in each regression.
Regressions using the underlying EFNA3 subcomponent data reveal that increasing government employment (as a percent of total employment) is negatively (-0.095) and significantly (at the 5% level) associated with the bottom 90% income rate of growth.
(19.) Results from regressions on the subcomponents of EFNA3 are not reported in the tables, but are available upon request.
Sales Taxes Collected as a Percentage of GDP Area 3 (EFNA3).
The EFNA composite index is comprised of three area indices: size of government (EFNA1); distortionary taxation and takings (EFNA2); and labor market freedom (EFNA3).
Columns 2, 3, and 4 report results using each of the three economic freedom areas: size of government (EFNA1), distortionary taxation (EFNA2), and market freedom (EFNA3).
Among the freedom variables, EFNA and EFNA3 have the most economically significant partial correlation with the level of development, as a standard deviation increase in overall economic freedom and labor market freedom are both associated with a two-thirds standard deviation increase in LRGDPL.
Economically, EFNA3 has the strongest correlation among the freedom variables, as a standard deviation increase in labor market freedom is associated with a 1.34 standard deviation decline in the unemployment rate.
In column 5, EFNA1 and EFNA3 both enter negatively and significantly significant at the 10 percent level or better.
Among the economic freedom variables, EFNA, EFNA1, and EFNA3 are statistically significant at the 5 percent level or better, and each enters positively.
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