EDEM3
EDEM3
A gene on chromosome 1q25 that encodes an enzyme which accelerates endoplasmic reticulum-associated degradation (ERAD), extracting misfolded—but not productively folded—glycoproteins from the calnexin cycle and targeting them for degradation by proteasomes. It is thought to have mannosidase activity.Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.