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A gene on chromosome 16q12.1 that encodes a cytoplasmic protein with deubiquitinating activity and plays a key role in regulating pathways leading to NF-kappa-B activation, which affects cell survival, proliferation and differentiation.

Molecular pathology
CLYD mutations are causatively linked to cylindromatosis, multiple familial trichoepithelioma and Brooke-Spiegler syndrome.
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'According to World Bank Ease of Doing Business report (2018), the EAC is ranked at 149 out of 190 in the ease of trading across borders, as EABC, we will coordinate, set the agenda and facilitate evidence-based research on Public Private Dialogues to reducing barriers to trade in the EAC region,' said Mathuki said.
Under Article 146 of the EAC treaty, a member state may be suspended from taking part in any EAC activities if it fails to observe and fulfill the fundamental principles and objectives of the treaty, including failure to meet financial commitments within 18 months.
The post EAC workers urged to curb pay rise demands appeared first on Cyprus Mail .
If the only people with a political interest in keeping the EAC project alive are the East African Legislative Assembly (EALA), their ineffectiveness in diplomacy during this moment shows that the EAC is far weaker than many people have imagined.
After finding JNK and TGF-beta pathways to be overactive only in EAC biopsies, they then incubated EAC tumour cells with therapeutic small molecules designed to block the pathways.
Atif Rehman Mian, Professor of Economics, Public Policy and Finance at Princeton University, was the first to quit days after the formation of the EAC on September 1, 2018.
Following suit, London-based economist Dr Imran Rasul had quitted the council, saying, 'With a heavy heart, I have resigned from the EAC this morning.'
He announced his decision in a tweet, explaining that the withdrawal of Dr Atif Mian's name by the government from the EAC because of his faith was against his principles.
Mian's appointment as EAC member has stirred a controversy as he belongs to the Ahmadi community.
The petitioner cited Prime Minister through Principal Secretary, Secretary Finance, Secretary Law, Secretary Interior, Secretary Defense, Chairman National Data and Registration Authority (NADRA) and Dr Arif Mian member EAC as respondents.
OBJECTIVE: To describe the clinical manifestations of external auditory canal (EAC) cholesteatoma and evaluate the surgical outcomes of reconstruction using an inferior pedicled soft-tissue periosteum flap.