CACNB4

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CACNB4

A gene on chromosome 2q22-q23 that encodes a beta subunit of a voltage-dependent calcium channel, which plays a regulatory role in calcium channel function by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling alpha-1 subunit membrane targeting.

Molecular pathology
CACNB4 mutations have been associated with idiopathic generalised epilepsy and juvenile myoclonic epilepsy.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The second order factor model suggests that by correlating the error terms eb1 and eb4, ea3 and ea5, ea6 and ea7 and further a cross correlation between ea4 and eb3 is necessary to obtain a model of respectable fit.
FACE fuel blends (Blend description: First letter: Ethanol, Second letter: FACE fuel type, Third digit: Ethanol percentage in the blend) Fuel blends FACE I (%) FACE J (%) FACE A (%) Ethanol (%) EIO 100 -- -- 0 EI2 98 -- -- 2 EI5 95 -- -- 5 EI10 90 -- -- 10 EI15 85 -- -- 15 EI20 80 -- -- 20 EJO -- 100 -- 0 EJ2 -- 98 -- 2 EJ5 -- 95 -- 5 EJ10 -- 90 -- 10 EJ15 -- 85 -- 15 EJ20 -- 80 -- 20 EAO -- -- 100 0 EA2 -- -- 98 2 EA5 -- -- 95 5 EA10 -- -- 90 10 EA15 -- -- 85 15 EA20 -- -- 80 20 Table A2.
This is related to EA5 Application Development or Procurement Methodology, which is discussed below.
Fractions were combined according to similarity in TLC using Naturstoff A (5% (m/v) in Me0H) and anisaldehyde reagent (0.5% anisaldehyde, 84.5% Me0H, 10% glacial acetic acid, 5% sulphuric acid (98%), each v/v) as spray reagent for detection and resulted in 1.74g EA1 (~0-800 ml), 0.15 g EA2 (~800-850 ml), 2.29 g EA3 (~850-1000 ml), 0.70 g EA4 (~1000-1100 ml), 0.47 g EA5 (~1100-1300 ml) and 0.50g EA6 (~1300-1800 ml).
Contenido del Cuestionario de salud y bienestar de ninos(as) y adolescentes de 8 a 18 anos KIDSCREEN-27 Dominio Item y contenido resumido del item Actividad fisica y salud (AF) AF1 Salud general AF2 Bien de salud AF3 Fisicamente activo AF4 Correr AF5 Energia Estado de animo y EA1 Disfrutado sentimientos (EA) EA2 Buen humor EA3 Divertido EA4 Triste EA5 Sentido tan mal EA6 Solo EA7 Contento Vida familiar y tiempo FL1 Tiempo para ti libre (FL) FL2 Tiempo libre FL3 Padres tiempo FL4 Padres justos FL5 Hablar padres FL6 Dinero amigos FL7 Dinero gastos Apoyo social y amigos (AM) AM1 Tiempo amigos AM2 Divertido amigos AM3 Ayuda amigos AM4 Confiar amigos Entorno escolar (EC) EC1 Feliz colegio EC2 Bien colegio EC3 Atencion clase EC4 Bien profesores Tabla 2.
The deal allow Global Petroleum with a continuing right to convert its investment in the project to date into a 25 percent legal and beneficial interest in Uganda License EA5.