CACNA1A

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CACNA1A

A gene on chromosome 19p13 that encodes the alpha-1A subunit of a voltage-dependent P/Q-type calcium channel, which mediates the entry of calcium ions into excitable cells. These channels are also involved in various calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and apoptosis.

Molecular pathology
CACNA1A mutations are associated with familial hemiplegic migraine and episodic ataxia 2.
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In addition to EA2, the CACNA1A gene is implicated in at least two other autosomal dominant neurological disorders: familial hemiplegic migraine type 1 (FHM1) and spinocerebellar ataxia type 6 (SCA6).
The I/H ratios were higher in the control, sham, EA1, and EA2 groups than in the normal group on the eighth day after reperfusion (all p < 0.001; Table 1, Figure 1, n = 6).
* The fact that we needed more supply air points worked out well because two of our exhaust points, EA1 and EA2 in Figure 4, could not be made to work due to architectural constraints.
The program Rodas de Conversa (Conversation Circles) aims to promote greater interaction and cooperation between EA2 and course coordinations, in light of its fundamental objective: the improvement in undergraduate teaching at UNICAMP.
The experimental syllogisms used were: AI1, EA1, EA2, AE2, IA3, AI3, IA4, AE4.
Interestingly, the GALNAC-T8, -T9, and -T18 enzymes do not have catalytic activity toward classic peptide substrates, which are derived from mucin 1 (MUC1) variant MUC1/A, MUC5AC, and mono-GalNAc/Thr7th-EA2 (a glycopeptide containing 1 GalNAc in the threonine at the 7th position, named EA2) (31), suggesting that the GALNAC-T members of this subfamily may glycosylate very specific substrates.
At the conclusion of EA2, I reviewed the course evaluation scores for items similar to all other courses.
100% hexane (EA1), hexane: ethyl acetate (9:1, EA2), hexane: ethyl acetate (8:2, EA3) and residual methanol soluble part (EA4) were collected.
Fractions were combined according to similarity in TLC using Naturstoff A (5% (m/v) in Me0H) and anisaldehyde reagent (0.5% anisaldehyde, 84.5% Me0H, 10% glacial acetic acid, 5% sulphuric acid (98%), each v/v) as spray reagent for detection and resulted in 1.74g EA1 (~0-800 ml), 0.15 g EA2 (~800-850 ml), 2.29 g EA3 (~850-1000 ml), 0.70 g EA4 (~1000-1100 ml), 0.47 g EA5 (~1100-1300 ml) and 0.50g EA6 (~1300-1800 ml).
Solo una de las preguntas dio una baja correlacion, y fue la EA2, que cuestiona sobre si has estado de buen humor, un termino que pudo haberse prestado para confusiones en nuestra poblacion, en la cual el termino humor puede prestarse a otras interpretaciones, mas como a gracioso que respecto a un estado de animo.
The group alleged that the HVAC system was not sufficient and that the project does not meet LEED prerequisites EA1, EA2, and EQ1.