ETV4

(redirected from E1AF)

ETV4

A gene on 17q21 that encodes a transcription activator that binds to the adenovirus E1A gene enhancer, specifically at the core-binding sequence 5'[AC]GGA[AT]GT-3'.
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References in periodicals archive ?
cells: identification of E1AF as important transcription activator.
Shen et al., "Elevated [beta]1,4-galactosyltransferase I in highly metastatic human lung cancer cells: identification of E1AF as important transcription activator," Journal of Biological Chemistry, vol.
(23) Less-common cytogenetic variants, however, have also been identified and are characterized by the fusion of the EWSR1 gene with other members of the ETS family of transcription factors, including ERG (21q22), ETV1 (7p22), E1AF (17q21), and FEV (2q35-36).
(39) Other variant translocations reported in bone EFT accounting for less than 1% of cases include t(7;22)(p22; q12), t(17;22)(q12;q12), and t(2;22)(q23;q12), involving fusion of EWS to ETV1, E1AF, and FEV genes, respectively (Table 2).