Dupuytren's contracture

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abnormal shortening of muscle tissue, rendering the muscle highly resistant to stretching; this can lead to permanent disability. It can be caused by fibrosis of the tissues supporting the muscle or the joint, or by disorders of the muscle fibers themselves.

Improper support and positioning of joints affected by arthritis or injury, and inadequate exercising of joints in patients with paralysis can result in contractures. For example, a patient with arthritis or severe burns may assume the most comfortable position and will resist changing position because motion is painful. If the joints are allowed to remain in this position, the muscle fibers that normally provide motion will stretch or shorten to accommodate the position and eventually will lose their ability to contract and relax.

In many cases contractures can be prevented by range of motion exercises (active or passive), and by adequate support of the joints to eliminate constant shortening or stretching of the muscles and surrounding tissues.
Dupuytren's contracture a flexion deformity of the fingers or toes, due to shortening, thickening, and fibrosis of the palmar or plantar fascia.
ischemic contracture muscular contracture and degeneration due to interference with the circulation due to pressure or to injury or cold.
Volkmann's contracture contraction of the fingers and sometimes of the wrist, or of analogous parts of the foot, with loss of power, after severe injury or improper use of a tourniquet or cast in the region of the elbow.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


(kon-trak'chur) [L. contractura, a drawing together]
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Fibrosis of connective tissue in skin, fascia, muscle, or a joint capsule that prevents normal mobility of the related tissue or joint. See: illustration

Dupuytren's contracture

See: Dupuytren's contracture

fibrotic contracture

Contraction of a muscle in which the muscle tissue has been replaced by fibrous tissue because of injury.

functional contracture

Contraction of a muscle that decreases during anesthesia or sleep.

myostatic contracture

Adaptive shortening of muscle, usually caused by immobilization and without tissue pathology.

physiological contracture

A temporary condition in which tension and shortening of a muscle are maintained for a considerable time although there is no tetanus. It may be induced by injury, disease, heat, drug action, or acids.

pseudomyostatic contracture

An apparent permanent contraction of a muscle due to a central nervous system lesion, resulting in loss of range of motion and resistance of the muscle to stretch.

Volkmann's contracture

See: Volkmann, Richard von
Medical Dictionary, © 2009 Farlex and Partners

Dupuytren's contracture

Shortening of some of the tendons on the palm of the hand, as a result of inflammation, so that one or more fingers are pulled into a permanently bent position. The ring finger is usually the first to be affected. Treatment is by careful surgical removal of the thickened, contracted tissue. The condition is unrelated to manual labour. It is believed to be mediated by free radicals and is commoner in people with AIDS than in the general population. (Baron Guillaume Dupuytren, 1777–1835, French surgeon).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Over the years, most historians believed that the cause of his injured right hand was either a stroke or Dupuytren's disease, a condition that leads to contraction and deformation of the hand.
The injection of nodules of Dupuytren's disease with triamcinolone acetonide.
- US-based fibrosis treatments developer 180 Therapeutics LP has received positive results from a Phase 2a clinical trial of the anti-TNF monoclonal antibody, adalimumab, in patients suffering from Dupuytren's disease, the company said.
Summary: Washington DC, [USA] July 08 (ANI): Patients with incurable hand disabling condition, called Dupuytren's disease, have a ray of hope.
Dupuytren's disease [1] is a flexion contracture of the hand due to palmar fibromatosis, [2] in which the fingers bend towards the palm and cannot be fully extended (straightened).
Chan et al., "Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target," Proceedings of the National Academy of Sciences, vol.
He also compared Peyronie's disease with Dupuytren's disease, a condition where one or several fingers become permanently bent into a flexed position.
His areas of expertise includes surgery for nerve compressions such as carpal or cubital tunnel, Dupuytren's disease, tendon problems, osteoarthritis and rheumatoid arthritis, as well as hand, wrist and finger injuries.
They describe surgical exposures, techniques, and infections; fractures and dislocations; tendon pathologies and surgery; surgery for nerve disorders and deficits; surgery for arthritis; Dupuytren's disease, neoplasms, amputation, and vascular surgery; and hand surgery for trauma and congenital differences in children.
This study depicted a picture similar to Dupuytren's disease. According to the author this happens because of rise in collagen formation, myofibroblasts and fibroplasias.
Optimal functional outcome measures for assessing treatment for Dupuytren's disease: a systematic review and recommendations for future practice.