Dupuytren's contracture


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

contracture

 [kon-trak´cher]
abnormal shortening of muscle tissue, rendering the muscle highly resistant to stretching; this can lead to permanent disability. It can be caused by fibrosis of the tissues supporting the muscle or the joint, or by disorders of the muscle fibers themselves.

Improper support and positioning of joints affected by arthritis or injury, and inadequate exercising of joints in patients with paralysis can result in contractures. For example, a patient with arthritis or severe burns may assume the most comfortable position and will resist changing position because motion is painful. If the joints are allowed to remain in this position, the muscle fibers that normally provide motion will stretch or shorten to accommodate the position and eventually will lose their ability to contract and relax.

In many cases contractures can be prevented by range of motion exercises (active or passive), and by adequate support of the joints to eliminate constant shortening or stretching of the muscles and surrounding tissues.
Dupuytren's contracture a flexion deformity of the fingers or toes, due to shortening, thickening, and fibrosis of the palmar or plantar fascia.
ischemic contracture muscular contracture and degeneration due to interference with the circulation due to pressure or to injury or cold.
Volkmann's contracture contraction of the fingers and sometimes of the wrist, or of analogous parts of the foot, with loss of power, after severe injury or improper use of a tourniquet or cast in the region of the elbow.

contracture

(kon-trak'chur) [L. contractura, a drawing together]
Enlarge picture
CONTRACTURE OF THE RIGHT HAND
Fibrosis of connective tissue in skin, fascia, muscle, or a joint capsule that prevents normal mobility of the related tissue or joint. See: illustration

Dupuytren's contracture

See: Dupuytren's contracture

fibrotic contracture

Contraction of a muscle in which the muscle tissue has been replaced by fibrous tissue because of injury.

functional contracture

Contraction of a muscle that decreases during anesthesia or sleep.

myostatic contracture

Adaptive shortening of muscle, usually caused by immobilization and without tissue pathology.

physiological contracture

A temporary condition in which tension and shortening of a muscle are maintained for a considerable time although there is no tetanus. It may be induced by injury, disease, heat, drug action, or acids.

pseudomyostatic contracture

An apparent permanent contraction of a muscle due to a central nervous system lesion, resulting in loss of range of motion and resistance of the muscle to stretch.

Volkmann's contracture

See: Volkmann, Richard von

Dupuytren's contracture

Shortening of some of the tendons on the palm of the hand, as a result of inflammation, so that one or more fingers are pulled into a permanently bent position. The ring finger is usually the first to be affected. Treatment is by careful surgical removal of the thickened, contracted tissue. The condition is unrelated to manual labour. It is believed to be mediated by free radicals and is commoner in people with AIDS than in the general population. (Baron Guillaume Dupuytren, 1777–1835, French surgeon).
References in periodicals archive ?
'My hands are everything to me, but when I was diagnosed with Dupuytren's contracture nearly 15 years ago, I waited to get treatment because I assumed surgery was my only option,' said Elway.
Spence, "Keloid scarring, but not Dupuytren's contracture, is associated with unexplained carotid atherosclerosis," Clinical and Investigative Medicine, vol.
Xiapex (collagenase clostridium histolyticum), is a pharmacological treatment for Peyronie's disease and Dupuytren's contracture and may be an alternative to invasive and often complicated surgery for patients.
Injection of collagenase Clostridium his tolyticum in patients with early-stage Dupuytren's contracture resulted in significantly better clinical outcomes than those that were seen in patients with advanced disease.
Recent XIAFLEX Dupuytren's Contracture Highlights: As reported by Auxilium, U.S.
Xiaflex is approved by the FDA and the EMA as a treatment for Dupuytren's contracture, and is also in development in Japan.
A diabetic patient presenting with stiff hand following fasciectomy for Dupuytren's contracture: A case report.
eileen Calder, Newcastle a: It sounds like he has Dupuytren's contracture, a common condition caused when tissue thickens in the palm due to an overgrowth of collagen.
Collagenase Clostridium histolyticum (Xiaflex; B) is given intramuscularly for the treatment of Dupuytren's contracture with a palpable cord.
Dupuytren's contracture, an often painless but sometimes debilitating condition that causes one or more fingers to be pulled toward the palm, was identified in 1831 and affects as many as 2 million Americans, many of them Caucasian men over the age of 40.
Your symptoms match those of Dupuytren's contracture, a sometimes disabling (but not dangerous) condition that pulls fingers toward the palm and locks them there.