Dukes' classification

Dukes' classification

 [do̳ks]
a system of staging colorectal tumors based on evaluation of the depth of invasion of the carcinoma and the presence or absence of metastasis. The four stages are: A, confined to the mucosa and submucosa; B, invasion through the muscularis without lymph node involvement; C, invasion through the muscularis with regional node metastasis; and D, tumor metastasis to distant sites. See illustration.
 Modified Dukes' staging system for colorectal cancer. From Aspinall and Taylor-Robinson, 2001.
References in periodicals archive ?
On comparing the distribution of cases by Dukes' classification, they found a preponderance of Dukes' C tumors in patients undergoing APR and a relatively higher proportion of Dukes' A and B lesions in those undergoing AR.
Study design and validity Patients were stratified by site of cancer and Dukes' classification. They were then randomized to intensive or standard follow-up; both groups were similar in age, sex, and tumor differentiation.
The type of follow-up was also not a predictor of survival in any subgroup analysis, as when controlling for adherence of tumor, Dukes' classification, or the tumor site (P = .19).