Duke's classification

Duke's classification

Surgical oncology A system for staging colorectal carcinoma–which has been modified with time. See TNM classification.
Duke's classification
Stage Depth of invasion 5-year survival
A  Limited to mucosa  100.0%
B1  Muscularis propria, negative nodes  66.4%
B2  Penetrates muscularis propria, negative nodes   53.9%
C1  Limited to wall, positive nodes  42.8%
C2  Through wall, positive nodes  22.4%
(D) Non-Duke's designation for distal metastases    3.0%
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References in periodicals archive ?
No correlations of preoperative serum PRL-3 levels in colorectal cancer patients with age, gender, tumor localization, histological type, stage, local lymph node involvement, distant organs metastases and Duke's classification were observed.
Detection of PRL-3 protein in the preoperative serum of patients with colorectal cancer
With A being the least and D the biggest risk, using the Duke's classification, Susan was found to be a level C.
I got new lease of life from my cancer battle; 'Positive' Susan got fit and lost EIGHT stone: MUM'S AMAZING FIGHTBACK FROM DEADLY CONDITION

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