Duffy blood group


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Duffy blood group

a red blood cell ANTIGEN found in certain human racial groups, controlled by a single autosomal gene on chromosome 1. Around 65% of Caucasians and 99% of Chinese are positive for the antigen being either homozygous or heterozygous for the allele Fy+, while 92% of West Africans are not, being homozygous for Fy- alleles.

Duffy,

surname of the patient in whom this antigen was first found in 1950.
Duffy antigen - may be related to resistance to malarial infection.
Duffy blood group
References in periodicals archive ?
From malaria to chemokine receptor: the emerging physiologic role of the Duffy blood group antigen.
Relationship between Duffy blood groups genotypes and malaria infection in different ethnic groups of Choco- Colombia.
The value of DNA analysis for antigens in the Duffy blood group system.
The coding sequence of Duffy blood group gene in humans and simians: restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals.
Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus.
Complex signatures of natural selection at the Duffy blood group locus.