Ductal adenocarcinoma

Ductal adenocarcinoma

A malignant tumor arising from the duct cells within a gland.
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Pancreatic ductal adenocarcinoma (PDA) affects an estimated 57,000 Americans annually and kills about 45,000, according to the American Cancer Society, making it the fourth leading cause of cancer death in the U.S.
* 5 July: Presentation at ESMO-GI of promising interim data from the Phase 1/2 study of the investigational use of Onivyde[R] in combination with 5-fluorouracil/leucovorin (5-FU/LV) and oxaliplatin (OX) in study patients with previously untreated metastatic pancreatic ductal adenocarcinoma cancer (PDAC)
France-based Ipsen and Servier have revealed preliminary data from the Phase 1/2 study of the investigational use of liposomal irinotecan (ONIVYDE) in combination with five- fluorouracil/leucovorin (5-FU/LV) and oxaliplatin (OX) in study patients with earlier untreated metastatic pancreatic ductal adenocarcinoma cancer, at the ESMO 21st World Congress on Gastrointestinal Cancer in Barcelona, Spain it was reported yesterday.
Therefore, there has been an effort to differentiate ITPN from other intraductal pancreatic lesions such as IPMN or pancreatic ductal adenocarcinoma with a focus on the immunohistochemical and clinicopathologic features (5-8).
Besides PIN, other differential diagnoses for IDC-P include intraductal spread by urothelial carcinoma and ductal adenocarcinoma. (45) In challenging situations, confirmation of an intraductal urothelial carcinoma can be facilitated by immunohistochemical staining (p63, GATA3, and uroplakin 2-positive lesional cells).
An ex vivo live tissue sensitivity assay was performed with a panel of 20 pancreatic ductal adenocarcinoma patient-derived xenografts to study the overall activity of BP1003 alone, and in combination with gemcitabine.
Evaluation of Mesothelin BiTE Antibody Constructs in Models of Pancreatic Ductal Adenocarcinoma
WHO 2010 sets undifferentiated carcinoma with osteoclast-like giant cell and pleomorphic giant cell as a pancreatic ductal adenocarcinoma variant, although UCOGC is a tumor with a much better prognosis [16].
Here, we would like to present an interesting case, who had history of breast surgery due to diagnosis of invasive ductal adenocarcinoma and was diagnosed with breast amyloidosis presented with a mass and with micro-calcifications on the operation site.
New York, NY, December 29, 2018 --(PR.com)-- Pancreatic cancer (scientifically known as Pancreatic ductal adenocarcinoma) is the most common subtype of human pancreatic cancer.
However, its prognostic significance in pancreatic ductal adenocarcinoma (PDAC) needs support of further evidence.
MONDAY, June 4, 2018 (HealthDay News) -- The oxaliplatin, leucovorin, irinotecan, and 5-fluorouracil (mFOLFIRINOX) regimen is associated with longer median disease-free and overall survival in pancreatic ductal adenocarcinoma; and, receiving chemotherapy before surgery is associated with better disease-free survival, according to two studies presented at the annual meeting of the American Society of Clinical Oncology, held from June 1 to 5 in Chicago.