keratoconjunctivitis sicca

(redirected from Dry eye disease)

keratoconjunctivitis

 [ker″ah-to-kon-junk″tĭ-vi´tis]
inflammation of the cornea and conjunctiva.
epidemic keratoconjunctivitis a highly infectious form, commonly with regional lymph node involvement, occurring in epidemics; an adenovirus has been repeatedly isolated from affected patients.
phlyctenular keratoconjunctivitis a form marked by formation of a phlyctenule (small lesion) at the corneal limbus.
keratoconjunctivitis sic´ca a condition marked by hyperemia of the conjunctiva, thickening and drying of the corneal epithelium, and itching and burning of the eye. Called also dry eye.

ker·a·to·con·junc·ti·vi·tis sic·ca

keratoconjunctivitis associated with decreased tears.
See also: Sjögren syndrome.
Dryness of eyes, often due to decreased tear secretion, which occurs in Sjögren syndrome, autoimmune disorders—systemic lupus, rheumatoid arthritis, scleroderma, sarcoidosis—amyloidosis, hypothyroidism, vitamin A deficiency, and in periorbital lymphoproliferative disorders

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring, due to deficit of the aqueous component of tears.
Synonym(s): dry eye syndrome.

keratoconjunctivitis sicca

Dry eye. A state of inadequate wetting and lubrication of the cornea as a result of defective tear production. This results from damage to the tear glands by the same AUTOIMMUNE DISEASE process that causes RHEUMATOID ARTHRITIS, SJOGREN'S SYNDROME, systemic lupus erythematosus and other related conditions. Dry eye is common in all these disorders. There is constant discomfort, foreign-body sensation and sometimes pain and the condition may progress to infection and ulceration of the cornea. Treatment is by the regular use of artificial tears.

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring.
Synonym(s): dry eye syndrome.
References in periodicals archive ?
The NDA for KPI-121 0.25% included data from one Phase 2 and two Phase 3 efficacy and safety trials, STRIDE 1 and STRIDE 2, studying approximately 2,000 patients with dry eye disease.
Food and Drug Administration (FDA) regarding the Company's new drug application (NDA) for KPI-121 0.25% for the temporary relief of the signs and symptoms of dry eye disease.
"Our experience with INVELTYS provides a strong foundation as we advance KPI-121 0.25%, our product candidate for dry eye disease, which, if approved, we believe will be a promising new therapy for the millions of patients who experience episodic dry eye flares." The PDUFA action date for KPI-121 0.25% is August 15, 2019.
KPI-121, 0.25%, is Kala's candidate for the temporary relief of signs and symptoms of dry eye disease using a two-week course therapy.
The product is claimed to be the first and only prescription treatment to secure approval for both signs and symptoms of dry eye disease, with a mechanism of action that targets inflammation.
The hot and cold therapy eye mask contains ThermaBeads to relieve symptoms associated with blepharitis, dry eye disease and meibomian gland dysfunction.
[USPRwire, Thu Feb 21 2019] A new report titled " Dry Eye Disease Market Outlook and Growth Analysis for the Period 2025 -- By MRRSE " has been included in the enormous research repository of Market Research Reports Search Engine (MRRSE) that compiles various facets of the Dry Eye Disease Market at a global level portraying a holistic analysis of the marketplace along with intelligence on key participants.
Talk to your doctor as occasional bouts of dry eyes can eventually progress into dry eye disease, Locy noted.
Asbell, M.D., from the Icahn School of Medicine at Mount Sinai in New York City, and colleagues randomized patients with moderate-to-severe dry eye disease to receive a daily oral dose of 3,000 mg of fish-derived n-3 eicosapentaenoic and docosahexaenoic acids (329 patients) or an olive oil placebo (170 patients).
Ocular surface disease is an umbrella term that includes a variety of complex pathologies such as Stevens-Johnson syndrome, mucous membrane pemphigoid, limbal stem cell insufficiency, dry eye disease, and ocular graft-versus-host disease.