keratoconjunctivitis sicca

(redirected from Dry eye disease)

keratoconjunctivitis

 [ker″ah-to-kon-junk″tĭ-vi´tis]
inflammation of the cornea and conjunctiva.
epidemic keratoconjunctivitis a highly infectious form, commonly with regional lymph node involvement, occurring in epidemics; an adenovirus has been repeatedly isolated from affected patients.
phlyctenular keratoconjunctivitis a form marked by formation of a phlyctenule (small lesion) at the corneal limbus.
keratoconjunctivitis sic´ca a condition marked by hyperemia of the conjunctiva, thickening and drying of the corneal epithelium, and itching and burning of the eye. Called also dry eye.

ker·a·to·con·junc·ti·vi·tis sic·ca

keratoconjunctivitis associated with decreased tears.
See also: Sjögren syndrome.

keratoconjunctivitis sicca

dryness of the cornea caused by a deficiency of tear secretion in which the corneal surface appears dull and rough and the eye feels gritty and irritated. The condition may be associated with erythema multiforme, Sjögren's syndrome, trachoma, and vitamin A deficiency. Methylcellulose artificial tears may give some relief, as can insertion of plugs into the punctae and use of cyclosporine drops.
Dryness of eyes, often due to decreased tear secretion, which occurs in Sjögren syndrome, autoimmune disorders—systemic lupus, rheumatoid arthritis, scleroderma, sarcoidosis—amyloidosis, hypothyroidism, vitamin A deficiency, and in periorbital lymphoproliferative disorders

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring, due to deficit of the aqueous component of tears.
Synonym(s): dry eye syndrome.

keratoconjunctivitis sicca

Dry eye. A state of inadequate wetting and lubrication of the cornea as a result of defective tear production. This results from damage to the tear glands by the same AUTOIMMUNE DISEASE process that causes RHEUMATOID ARTHRITIS, SJOGREN'S SYNDROME, systemic lupus erythematosus and other related conditions. Dry eye is common in all these disorders. There is constant discomfort, foreign-body sensation and sometimes pain and the condition may progress to infection and ulceration of the cornea. Treatment is by the regular use of artificial tears.

ker·a·to·con·junc·ti·vi·tis sic·ca

(ker'ă-tō-kŏn-jŭngk'ti-vī'tis sik'ă)
A chronic mucopurulent conjunctivitis, sometimes leading to corneal ulceration and scarring.
Synonym(s): dry eye syndrome.

keratoconjunctivitis sicca (ker´ə-tōkənjungk´tivī´tis sik´ə),

keratoconjunctivitis

inflammation of the cornea and conjunctiva.

chronic immune-mediated keratoconjunctivitis syndrome
see chronic superficial keratitis.
infectious keratoconjunctivitis
see also infectious bovine kerato conjunctivitis. Caused by Moraxella bovis, Histoplasma capsulatum, Chlamydiae, Mycoplasma spp.
proliferative keratoconjunctivitis
see nodular fasciitis.
keratoconjunctivitis sicca
a condition marked by hyperemia of the conjunctiva, thickening and drying of the corneal epithelium, secondary to quantitative and qualitative deficiencies in the tear film. Deep keratitis and corneal ulceration may occur. Often a tenacious, stringy mucoid discharge accumulates in the conjunctival sac. Called also dry eye.
References in periodicals archive ?
PPL will be advancing its lead candidate, PPL-003, to an Investigational New Drug (IND) application for the topical treatment of dry eye disease and uveitis.
NICE Recommends the Use of IKERVIS in England for the Treatment of Severe Keratitis in Adult Patients with Dry Eye Disease
9% after the drug group reported the successful trial of its new dry eye disease treatment, Lifitegrast.
Shire's OPUS-3 Phase 3 Trial with Lifitegrast Meets Primary and Key Secondary Endpoints, Significantly Reducing Patient-Reported Symptoms for Dry Eye Disease
Food and Drug Administration (FDA) requested an additional clinical study as part of a complete response letter (CRL) to the company s new drug application for lifitegrast for the signs and symptoms of dry eye disease in adults.
InflammaDry is said by PI to be the first and only, rapid, in-practice test which detects MMP-9, a biomarker for inflammation that is consistently elevated in the tears of patients with dry eye disease.
To understand patients' eye strain, which is one of major symptoms of dry eye disease, it is important that ophthalmologist pay attention to MUC5AC concentration in tears," said Dr.
The four are irritable bowel syndrome, musculoskeletal pain, pelvic pain and dry eye disease.
Dry eye disease (DED) is a multi-factorial disorder of the tear film and ocular surface resulting in discomfort, visual disturbance and ocular surface damage.
Later topics of the 19 papers focus on the role the innate immune system plays in dry eye disease, herpes simplex virus, glaucoma, uveitis, macular degeneration, and corneal transplantation.
Several studies have determined an association between the intake of omega-3 supplements and meibomian gland oils and the implication for dry eye disease.
LipiView measures the absolute thickness of the lipid layer of a dry eye patient's tear film while LipiFlow treats the root cause of evaporative dry eye disease by unblocking obstructed Meibomian glands during an in-office procedure.