lead optimization

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lead optimization

(lēd)
The synthetic refinement of a candidate drug from its crude or original state into an agent that is safer, more useful, or more marketable.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
M2 PRESSWIRE-August 29, 2019-: Asia Pacific Drug Development Markets, 2026 By Mode, Process Step, & Therapeutic Area
Cesano has more than 25 years' experience of drug development, regulatory and medical affairs activities.
17 June 2019 - Ohio, US-based drug development and commercialisation partner Camargo Pharmaceutical Services has agreed to acquire Montreal-based drug development partner InSymbiosis to improve R and D outsourcing with biopharma companies, the company said.
LabCorp says its Covance Drug Development segment agreed to buy Envigo's non-clinical research services business, while Envigo's Research Models Services business will acquire the Covance Research Products business.
Lenox will be responsible for leading LGM's drug development unit's sales, business development and marketing team.
Drug development is a costly and time-consuming endeavor with high potential risks.
London, United Kingdom, October 24, 2015 --(PR.com)-- Global drug development is changing as paediatric drug development has become an essential part of it, with the need to obtain paediatric information for medicines used in children being a consensus in the EU.
"Our understanding of human genetics is rapidly expanding, and there is growing recognition that the elucidation of the genetic causes of disease will have a transformative effect on both patient care and drug development in many different diseases," says David Goldstein, PhD, founding director of Columbia University's Institute for Genomic Medicine.
The continuing evolution of new technologies, such as 3-D biological printing, ultra-high-resolution analytical instruments, next-generation sequencing, desktop electron microscopy, gene therapy, translational research, stem cell therapies and microbiornics are changing the traditional rules for drug development, as well as the FDA (Food and Drug Administration) changing its own rules.
WEARSIDE pharmaceutical firm Onyx Scientific has been appointed by Cancer Research UK to manage several of its drug development projects.
NORDIC BUSINESS REPORT-May 27, 2014-BioInvent returns rights to ADC-1013 drug development candidate to Alligator Bioscience for undisclosed sum
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