Injury to dorsal root ganglia
alters innervation of spinal cord dorsal horn lamina involved in nociception.
(2011b; 2015; 2016) explored the role of local protein synthesis in regenerating axons, combined acetylcholinesterase and silver method for demonstrating motor endplates, and expression of Akt, MAPK, c-Jun and c-Fos in the dorsal root ganglia
in accelerating motor and sensory functional recovery after crush injury by H.
After each experimental period, time-matched euglycemic (E) or 4, 8, or 12 week-long diabetic rats (DB) (E4, E8, E12, DB4, DB8, and DB12, respectively) were sacrificed, and SN and dorsal root ganglia
(DRG) harvested for analysis of slc5A3 (SMIT1), slcA11 (SMIT2), and slc2A13 (HMIT) mRNA expression by RT-PCR and protein levels by western blot analyses.
In order to uncover the molecular reasons for the mole-rat's remarkable resistance to pain, the researchers took sensory tissue from the spinal cord and dorsal root ganglia
of all nine species studied.
"The same virus that causes varicella in children later reactivates after going dormant in the dorsal root ganglia
, and it reactivates as herpes zoster, which is 10 times more severe than chicken pox and leads to 10 times the health care costs.
"The signal goes from neuronal projections in the skin through the dorsal root ganglia
(DRG) - which are clusters of sensory cells located at the root of the spinal nerves - then to the spinal cord.
Hokfelt, "Distribution and regulation of [alpha]2-adrenoceptors in rat dorsal root ganglia
," Pain, vol.
Li et al., "Oxytocin-induced membrane hyperpolarization in pain-sensitive dorsal root ganglia
neurons mediated by [Ca.sup.2+]/nNOS/NO/[K.sub.ATP] pathway," Neuroscience, vol.
A study in streptozotocin diabetic rats found that insulin doses insufficient to induce changes in plasma glucose were still able to normalize rates of mitochondrial coupled respiration in cells from dorsal root ganglia
Reactivation of latent VZ acquired during previous episodes of VZV infection (chickenpox) and which have persisted in a latent form within the dorsal root ganglia
neural cells results in viral replication followed by spread of the virus down the sensory nerve to the skin/mucosa.
Dorsal root ganglia
(DRGs) were collected, incubated for 1h at 37[degrees]C with 0.125% collagenase (Sigma-Aldrich, Milan, IT), mechanically dissociated, and then plated onto glass coverslips precoated with 10 [micro]g/mL poly-L-lysine and 10 [micro]g/mL laminin (Sigma).
Both the left and the right dorsal root ganglia