Intravenous Remifentanil Activates Dorsal Motor Nucleus
of the Vagus (DMV).
"Neuroactive substances in the dorsal vagal complex of the medulla oblongata: nucleus of the tractus solitarius, area postrema, and dorsal motor nucleus
of the vagus." Neurochemistry International 7.1 (1985): 191-211.
The electrophysiologic study has shown that oxytocin is able to activate several neuronal population in different rat brain areas including the hypothalamic supraoptic nucleus, paraventricular nucleus, hippocampus and the dorsal motor nucleus
of the vagus nerve .
Histopathologic lesions in brain of zebu with spongiform encephalopathy and cow with bovine spongiform encephalopathy, Switzerland, 2004 * Site Cow Zebu Brainstem Dorsal motor nucleus
of vagus nerve (+) (++) Nucleus of spinal tract of trigeminal (++) (+++) nerve Nucleus of hypoglossal nerve (+) (++) Reticular formation (++) (++) Nucleus of solitary tract (++) (+++) Vestibular nuclei (++) (+) to (++) Olivary nuclei (++) (++) Cerebellar cortex (-) (+) Midbrain (substantia grisea centralis) (+) to (++) (++) to (+++) Thalamus (++) (++) to (+++) Hippocampus n.d.
Examination of the brains of these animals showed not only nigral cell loss with a corresponding striatal dopamine depletion but also neurodegeneration in the locus coeruleus, dorsal motor nucleus
of the vagus, and the nucleus basalis of Meynert, a pattern of cell loss that is strikingly similar to that seen in Parkinson's disease and is not observed in any other of the toxicant-induced animal models of Parkinson's disease.
Most authors agree that the reduction of RRIV in PD is due to degeneration of the dorsal motor nucleus
of the vagus nerve.
In patients with Parkinson's disease (PD), nonmotor symptoms such as hyposmia, mood disorders, sleep disorders, and autonomic abnormalities often precede motor symptoms, and [alpha]-synuclein deposition in the olfactory bulb, enteric plexus, or dorsal motor nucleus
of the vagus nerves is considered to proceed to nigral degeneration .