Dopamine receptor antagonists | definition of Dopamine receptor antagonists by Medical dictionary
Dopamine receptor antagonists
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Dopamine receptor antagonists (DAs)
The older class of antipsychotic medications, also called neuroleptics. These primarily block the site on nerve cells that normally receive the brain chemical dopamine.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive
Therefore, the D1-like dopamine receptor antagonist
SCH 23390 can block a short-term morphine-induced increase in c-fos expression in the nucleus accumbens and caudate putamen .
In a study by Daunais & McGinty (1996), selective D1 or D2 dopamine receptor antagonists
were used to investigate the transynaptic regulation of mRNAs coding for the opioid peptide, preprodynorphin, and the nuclear transcription factor, zif/268 after an acute cocaine binge.
Both classes of drugs are dopamine receptor antagonists
that work by blocking the action of naturally occurring dopamine in the brain.