dopamine receptor


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Related to dopamine receptor: dopamine receptor D2

dopamine receptor

Any of at least six receptors that bind dopamine in the brain. They influence body movements and emotional states. The dopamine receptors are designated D1, D2a, D2b, D3, D4, and D5. Each has an identifiably different function. The D2a receptor, for example, has a strong affinity for antipsychotic drugs, such as haloperidol.
See also: receptor
References in periodicals archive ?
Dr Ma added that because the probes could successfully track the internalisation process of dopamine receptors in cells, they also represent powerful tools for studying the role of dopamine receptors in the pathogenesis of cancer.
George, "Heteromeric dopamine receptor signaling complexes: emerging neurobiology and disease relevance," Neuropsychopharmacology, vol.
Quantitative real-time PCR (Q RT-PCR) was used blindly on the samples (ABI 7300; USA) using the Power SYBR Green PCR Master Mix (Applied Biosystems) to analyze the transcript levels of dopamine receptors in total volume 25 pl.
Role of dopamine receptors in the kidney in the regulation of blood pressure.
Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains.
Jones et al., "Impaired heme oxigenase activity, increased reactive oxygen species, and high blood pressure in D5 dopamine receptor deficient mice," The Journal of American Society of Nephrology, vol.
Dopamine receptors belong to the family of seven transmembrane domain G-protein coupled receptors (GPCR) [23-25].
injection of the dopamine receptor blocker haloperidol (1mg/kg) 5 min prior to the injection with [[sup.123]I]-1 (approximately 37 MBq).
D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes.
Drugs used in the treatment of the disease have the potential to cause extrapyramidal side effects by blocking D2 dopamine receptors mainly located in the striatum [4, 5].
Imaging of dopamine receptors in the nigrostriatal pathway under the influence of a typical antipsychotic drug reveals an almost total blockade (approaching 90% of receptor sites).