Autosomal dominant

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autosomal dominant

adjective Referring to a trait or disorder that may be passed from one generation to the next when only one allele is required to pass a genetic defect to the progeny.

Examples
Achondroplasia, Huntington’s disease, Marfan syndrome, neurofibromatosis, osteogenesis imperfecta.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

autosomal dominant

Genetics Referring to a mode of inheritance, in which the presence of only one copy of a gene of interest on one of the 22 autosomal–non-sex chromosomes, will result in the phenotypic expression of that gene; the likelihood of expressing an autosomal gene in progeny is 1:2; ♂ and ♀ are affected equally. Cf Autosomal recessive, X-linked recessive.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

autosomal dominant

Pert. to or characteristic of an autosomal dominant gene.
See: autosomal dominant gene
Medical Dictionary, © 2009 Farlex and Partners

Autosomal dominant or autosomal recessive

Refers to the inheritance pattern of a gene on a chromosome other than X or Y. Genes are inherited in pairs—one gene from each parent. However, the inheritance may not be equal, and one gene may overshadow the other in determining the final form of the encoded characteristic. The gene that overshadows the other is called the dominant gene; the overshadowed gene is the recessive one.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Also, there were no more types of dominance relationships considered, because the comparison of two settlements when the number of weakly dominated settlements, strongly dominated settlements, and number of settlements strongly dominating them are known would be difficult, eventually requiring equivalences of the dominance relationships.
The control was conducted to see if transferring the animals twice, and temporary separation from the opponent, could alone cause distabilization of the dominance relationship.
The experiment was performed to test whether chemical cues released during the initial formation of the dominance relationship affected its stability.
In the initial phase (P1), a dominance relationship was established, for which a significant difference (Wilcoxon signed-rank test: P [less than or equal to] 0.01) in dominance indices of dominants (97.9% [+ or -] 3.4%, n =12) and subordinates (20.5% [+ or -] 9.5%, n = 12) was found.
In P1, a dominance relationship was established; the dominance indices of the dominants (94.6% [+ or -] 6.5%, n = 14) were significantly higher than those of the subordinates (15.9% [+ or -] 13.6%, n = 14; Wilcoxon signed-rank test: P [less than or equal to] 0.01).
When the initial dominant and subordinate were separated--after they first established a dominance relationship and each animal was paired individually with a larger conspecific--we observed only one rank reversal; the differences in dominance indices between the original opponents remained significant when they reestablished their relationship.
Like most social animals, crayfish readily form dominance relationships and linear social hierarchies when competing for limited resources.
(2003) showed that stability and replication of dominance relationships in cichlid fish depend on the presence of other conspecifics.
Experiments 1 and 2 tested the possibility that an intruder crayfish, irrespective of its size, could disrupt established dominance relationships between a pair of crayfish.
Experiment 2 tested the effects of a same-sized intruder on established social dominance relationships. In the first phase (P1), dominance, as determined by dominance indices, was firmly established between the members of the original pair (DOM = 95.4% [+ or -] 7.3%, n = 12; SUB = 23.8% [+ or -] 9.7%, n = 12; Wilcoxon signed-rank test: P [less than or equal to] 0.01, Fig.
The underlying mechanisms of the observed destabilization of dominance relationships are still elusive.