Autosomal dominant

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autosomal dominant

adjective Referring to a trait or disorder that may be passed from one generation to the next when only one allele is required to pass a genetic defect to the progeny.

Achondroplasia, Huntington’s disease, Marfan syndrome, neurofibromatosis, osteogenesis imperfecta.

autosomal dominant

Genetics Referring to a mode of inheritance, in which the presence of only one copy of a gene of interest on one of the 22 autosomal–non-sex chromosomes, will result in the phenotypic expression of that gene; the likelihood of expressing an autosomal gene in progeny is 1:2; ♂ and ♀ are affected equally. Cf Autosomal recessive, X-linked recessive.

autosomal dominant

Pert. to or characteristic of an autosomal dominant gene.
See: autosomal dominant gene

Autosomal dominant or autosomal recessive

Refers to the inheritance pattern of a gene on a chromosome other than X or Y. Genes are inherited in pairs—one gene from each parent. However, the inheritance may not be equal, and one gene may overshadow the other in determining the final form of the encoded characteristic. The gene that overshadows the other is called the dominant gene; the overshadowed gene is the recessive one.
References in periodicals archive ?
The experiment was performed to test whether chemical cues released during the initial formation of the dominance relationship affected its stability.
In the initial phase (P1), a dominance relationship was established, for which a significant difference (Wilcoxon signed-rank test: P [less than or equal to] 0.
The dominance relationship remained stable throughout the next two experimental periods (in P2, DOM = 86.
As before, the two animals readily formed a firm dominance relationship during P1, as documented by the significant difference in their dominance indices (DOM = 99.
In P1, a dominance relationship was established; the dominance indices of the dominants (94.
Thus, the winning experience against the intruder may have empowered the original subordinates, which led to more agonistic success ("winner effect") when both animals reestablished their dominance relationship.
When the initial dominant and subordinate were separated--after they first established a dominance relationship and each animal was paired individually with a larger conspecific--we observed only one rank reversal; the differences in dominance indices between the original opponents remained significant when they reestablished their relationship.
This finding implied that loss of chemical (and possibly spatial) information from the initial formation of the dominance relationship started to affect rank stability.
Our analysis of reversal versus non-reversal fights suggests that important behavioral changes take place during the intruder period, changes that are predictive of the future stability of the dominance relationship.
Like most social animals, crayfish readily form dominance relationships and linear social hierarchies when competing for limited resources.
Experiments 1 and 2 tested the possibility that an intruder crayfish, irrespective of its size, could disrupt established dominance relationships between a pair of crayfish.
The underlying mechanisms of the observed destabilization of dominance relationships are still elusive.