In October 1939, Domagk
was awarded the Nobel prize for medicine but Hitler stopped him from collecting it and the Gestapo detained him for a week.
Author Thomas Hager, in his 2006 book about Domagk
, The Demon under the Microscope: From Battlefield Hospitals to Nazi Labs, One Doctor's Heroic Search for the World's First Miracle Drug, notes that sulfa saved the lives of Franklin Roosevelt's son and Winston Churchill.
Our study extends previous work that used data visualization, interactivity, and narratives to teach abstract and challenging curricula (c.f., Brodbeck, Mazza, and Lalanne 2009; Domagk
, Schwartz, and Plass 2010; Kennedy 2004; McCarthy 2012; Yarden and Yarden 2010).
Hager had never heard of Domagk
and was surprised to learn that he had won a Nobel Prize in 1939, and was arrested by the Gestapo when he tried to claim the prize.
Serial 10-[mu]m microtome sections were stained with Domagk
's stain (Romeis, 1968).
In 1935, the German chemist, Gerhard Domagk
, discovered that an azo dye, Prontosil, cured streptococcal infections in mice.
In the 1930s, Gerhard Domagk
and others discovered drugs like Prontosil and chemically synthesized molecules--called wonder drugs--which also destroy harmful bacteria.
Later, Gerhard Johannes Paul Domagk
(1895-1964), a German anatomic pathologist and bacteriologist, discovered that a red dye called prontosil rubrum protected laboratory animals from lethal doses of staphylococci and hemolytic streptococci.
At that time, decisions were made on the basis of individual cases, and the good of science--and possibly, future patients--was sacrificed for the benefit of the subject at hand. It is said that Domagk
, who was to win the Nobel Prize for his discovery of the red dye's bacteriostatic attributes, tried it on his own daughter for a streptococcal infection.
had found that the dye Prontosil had certain antibacterial properties (see 1932).
This dismal outlook on chemotherapy began to change when Gerhard Domagk
, a German pathologist and bacteriologist, found bacteriologic activity in a chemical derivative from oil dyes called sulfamidochrysoidine (also known as Prontosil).
Further, as demonstrated by previous research, pedagogical agents can be used in a wide range of instructional domains, including the humanities, mathematics, and science (e.g., Atkinson, 2002; Domagk
, 2010; Dunsworth & Atkinson, 2007; Johnson, Ozogul, Moreno, & Reisslein, 2013; Kizilkaya & Askar, 2008; Moreno, Mayer, Spires, & Lester, 2001; Ozogul, Johnson, Atkinson, & Reisslein, 2013).