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DOM

SOX10

A gene on chromosome 22q13.1 that encodes a member of the SOX (SRY-related HMG-box) family of transcription factors, which regulate embryonic development and determine cell fate. SOX10 may act as a transcription activator after forming a complex with other proteins; it acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development.

Molecular pathology
SOX10 mutations cause Waardenburg-Shah and Waardenburg-Hirschsprung disease.
References in periodicals archive ?
'DOM' is an original musical that will surely bring back good, old memories.
Today, DOM and UMMC can interact to share Consolidated-Clinical Document Architecture (C-CDA) patient summaries through UMMC's Epic EHR.
"Dom Hemingway" follows the conventions of the criminal redemption story and, at its heart, it tries to illustrate the emotional transformation of its lead character.
The Dom are also affected by the ongoing Israeli-Palestinian conflict.
The seven-course Dark Dinner Menu was eclectic and diverse and was created to compliment the different flavours present in Dom Perignon 2003.
Summary: The Dom people suffer from strong discrimination, live in extreme poverty and have poor access to education, said the first study conducted on the community in the country.
This was Dom Joly, the madcap star of Trigger Happy TV and ex-pupil of the Brummana High School near Beirut.