Ostrander, head of the dog genome
project at Fred Hutchinson, was among the first to appreciate the dog's potential as a model system for gene hunting.
Award (LANSING) 60 Michigan Hospitals Receive the Governor's Award of Excellence For Improving Patient Care PHTH027 05/20/2004 14:00 r f bc-PA-Air-Prod-Dividend (LEHIGH VALLEY) Air Products Increases Quarterly Dividend 26 Percent SFTH005 05/20/2004 14:00 r f bc-WA-Dog-Genome-Human (SEATTLE) Many Scientists Believe That the Dog Genome
Holds a Wealth of Information that Will Benefit Human Health SFTH056 05/20/2004 14:00 r f bc-CA-Maxygen-Gene-Disc (REDWOOD CITY) Maxygen Subsidiary Verdia Announces Discovery and Improvement of Glyphosate Tolerance Gene
Thanks to the recent completion of the dog genome
, faithful canine companions are one step closer to receiving better treatment and diagnostic options.
Brian McKernan's company, Agencourt Bioscience, and Broad Institute published the full sequence of a dog genome
An international team of researchers, which included scientists at the National Human Genome Research Institute, the University of Utah, Sundowners Kennels in Gilroy, California and Mars' Waltham Center for Pet Nutrition in the United Kingdom, studied simple genetic markers known as Single Nucleotide Polymorphisms, or SNPs, to find places in the dog genome
that correlate with breed traits.
With the dog genome
now fully mapped, scientists are discovering a range of potential benefits of DNA-based information on man's best friend.
Elaine Ostrander's lab at the National Institutes of Health's Dog Genome
The sequencing project revealed that the horse genome is somewhat larger than the dog genome
and smaller than the human and cow genomes.
The mapping of the dog genome
has big implications for both human and dog health, as both genomes are very similar.
The recent decoding of the dog genome
(SN: 9/27/03, p.
Therefore, continued studies of dog genome
variation and its impact of disease will hopefully lead to translational research and improved health care for humans as well as "man's best friend".
The report "has really very compelling data," says Elaine Ostrander, a molecular biologist at the Fred Hutchinson Cancer Research Center in Seattle who is collaborating oil a study of the dog genome