topoisomerase
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topoisomerase
[to″po-i´so-mer-ās]an enzyme involved in mobilization and replication of DNA during cell division.
to·po·i·so·mer·ase
(tō'pō-i-som'ĕr-ās),A type of enzyme converting (isomerizing) one topologic version of DNA into another; acts by catalyzing the breakage and reformation of DNA phosphodiester linkages.
[topo- + isomerase]
topoisomerase
(tō′pō-ī-sŏm′ə-rās′, -rāz′)n.
Either of two isomerase enzymes that alter the topology of DNA molecules by breaking and reconnecting coiled strands.