topoisomerase

(redirected from Dna topoisomerases, type i)
Also found in: Dictionary.

topoisomerase

 [to″po-i´so-mer-ās]
an enzyme involved in mobilization and replication of DNA during cell division.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

to·po·i·so·mer·ase

(tō'pō-i-som'ĕr-ās),
A type of enzyme converting (isomerizing) one topologic version of DNA into another; acts by catalyzing the breakage and reformation of DNA phosphodiester linkages.
[topo- + isomerase]
Farlex Partner Medical Dictionary © Farlex 2012

topoisomerase

(tō′pō-ī-sŏm′ə-rās′, -rāz′)
n.
Either of two isomerase enzymes that alter the topology of DNA molecules by breaking and reconnecting coiled strands.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.