Failure Oxybutynin (Ditropan
) 5 mg, 2-3 times per day to store Tolterodine 4 mg, daily (Detrusitol SR) Trospium (Uricon) 20 mg, twice daily Darifenacin(Enablex) 7.5-15 mg, daily Solifenacin (Vesicare) 5-10 mg, daily 2.
Oxybutynin is available in tablets (Ditropan
), extended-release tablets (Ditropan
XL), patch (Oxytrol) and gel form (Gelnique).
Some of the most dangerous (score three) drugs are commonly available and include the antihistamines chlorphenamine (used in the brand Piriton) and promethazine (used in Phenergan), anti-depressants amitriptyline (used in several brands) and paroxetine (used in Seroxat) and the incontinence drug oxybutynin (used in Ditropan
For example, codeine, ditropan
, probanthine, and aluminum-based antacids can cause constipation.
There are seven anticholinergics that are used as antispasmodics for the treatment of overactive bladder: darifenacin (Enablex) [C], fesoterodine (Toviaz) [C], flavoxate (Urispas) [B], oxybutynin (Ditropan
) [B], solifenacin (Vesicare) [C], tolterodine (Detrol) [C], and trospium (Sanctura) [C].
Patients may benefit from anticholinergic/ antimuscarinic drugs such as desmopressin nasal spray or tablets, tolterodine (Detro [R]), oxybutynin (Ditropan
[R]), or imipramine (Tofranil [R]).
The OROS(R) osmotic drug delivery technology provides controlled drug release over an extended period and has been employed as a sustained release formulation for many successful products, including CONCERTA(R), DITROPAN
XL(R), COVERA-HS(R), and PROCARDIA XL(R).
Oxybutynin, an anticholinergic tertiary amine, was approved in 1975 for treating overactive bladder, and is available in tablet, syrup and extended-release tablet formulations in trade (Ditropan
) and generic formulations.
This was the central issue in the Ditropan
XL [111 case.
, which is used for urinary incontinence, is one of the biggest offenders, in Dr.