ganglioside

(redirected from Disialoganglioside)
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ganglioside

 [gang´gle-o-sīd]
a class of galactose-containing cerebrosides found in central nervous system tissues; they are glycolipids of the basic composition ceramide-glucose-galactose-N-acetyl neuraminic acid. The form GM1 accumulates in tissues in generalized gangliosidosis, the form GM2 in Tay-Sachs disease.

gan·gli·o·side

(gang'glē-ō-sīd),
A glycosphingolipid chemically similar to cerebrosides but containing one or more sialic (N-acetylneuraminic or N-glycolylneuraminic) acid residues; found principally in nerve tissue, spleen, and thymus; ganglioside GM1 accumulates in generalized gangliosidosis; GM2 accumulates in Tay-Sachs disease.

ganglioside

/gan·glio·side/ (gang´gle-o-sīd) any of a group of glycosphingolipids found in the central nervous system tissues and having the basic composition ceramide-glucose-galactose-N -acetylneuraminic acid. The form GM1 accumulates in tissues in GM1 gangliosidoses and the form GM2 in GM2 gangliosidoses.

ganglioside

(găng′glē-ə-sīd′)
n.
Any of a group of galactose-containing cerebrosides found in the surface membranes of nerve cells.

ganglioside

[gang′glē·əsīd′]
a glycosphingolipid found in the brain and other nervous system tissues. Gangliosides are members of a group of galactose-containing cerebrosides with a basic composition of ceramide-glucose-galactose-N-acetyl neuraminic acid. Accumulation of gangliosides caused by an inborn error of metabolism results in gangliosidosis or Tay-Sachs disease.

gan·gli·o·side

(gang'glē-ō-sīd)
Glycosphingolipid chemically similar to cerebrosides but containing one or more sialic acid residues; found principally in nerve tissue, spleen, and thymus; GM1 accumulates in generalized gangliosidosis; GM2 accumulates in Tay-Sachs disease.

ganglioside

A compound of fat and carbohydrate (glycolipid) that is an important component in cell membranes.

Ganglioside

A fatty (lipid) substance found within the brain and nerve cells.
Mentioned in: Tay-Sachs Disease

ganglioside

a class of galactose-containing cerebrosides found in central nervous system tissues; they are glycolipids of the basic composition ceramide-glucose-galactose-N-acetyl neuraminic acid. The form GM1 accumulates in tissues in generalized gangliosidosis as observed in Friesian cattle, dogs and cats. The form GM2 accumulates in a similar disease of Yorkshire pigs, dogs and cats.
References in periodicals archive ?
After fixation with 40 g/L p-formaldehyde for 10 min, the slides were incubated for 30 min with 30 [micro]L of an unlabeled monoclonal mouse anti-human GD2 disialoganglioside antibody (clone 14.
Sela AS, Iliopus D, Guery DP, Herlyn D, Koprowski H (1989) Levels of disialogangliosides in sera of melanoma patients monitored by sensitive thin layer chromatography and immunostaining.
Five sphingoglycolipids have pyruvic acid and their acidity may be comparable to monosialo-or disialogangliosides.