Disease Modifying Anti-Rheumatic Drugs

Disease Modifying Anti-Rheumatic Drugs (DMARDs)

A class of antirheumatic drugs, including chloroquine, methotrexate, cyclosporine, and gold compounds, that influence the disease process itself and do not only treat its symptoms.
Mentioned in: Antirheumatic Drugs
References in periodicals archive ?
Several treatment options like painkillers, anti-inflammatory drugs and disease modifying anti-rheumatic drugs (DMARDS) are prescribed to ease pain and stiffness.
Objective: To determine the disease severity in patients with Rheumatoid Arthritis (RA), at baseline and the impact of treatment on disease activity (DA) after six months of disease modifying anti-rheumatic drugs (DMARDs) therapy.
The European Commission (EC) has granted marketing authorisation for the partnership's Kevzara (sarilumab) in combination with methotrexate (MTX) for treating moderately to severely active rheumatoid arthritis (RA) in adult patients who have responded inadequately to, or who are intolerant to one or more disease modifying anti-rheumatic drugs (DMARDs), such as MTX.
Conclusion: There was significant increase in both ESR and anti-CCP levels in rheumatoid arthritis patients on disease modifying anti-rheumatic drugs as compared with control group.
The CHMP recommended the use of Kevzara in combination with methotrexate (MTX) for the treatment of moderately to severely active RA in adult patients who have responded inadequately to, or who are intolerant to one or more disease modifying anti-rheumatic drugs (DMARDs).
Conversely, hydroxychloroquine in combination with corticosteroids or other disease modifying anti-rheumatic drugs (DMARDs) has been successful in treating chronic rheumatic manifestations.
Competition for Tumor Necrosis Factor Alpha (TNF-a) inhibitors is particularly fierce, and now dominates the treatment market for RA patients who are refractory to first-line Disease Modifying Anti-Rheumatic Drugs (DMARD).
Lauren is currently taking disease modifying anti-rheumatic drugs (DMARDs) to control her condition, however she still experiences fatigue and pain towards the end of the day.
compile 28 chapters for scientists and clinicians that detail the process and factors that influence chronic inflammation, outlining the systems biology of inflammation and regulatory mechanisms, including initiation, progression, and resolution; associated pathologies, such as cancer, chronic wounds, scarring, neuroinflammatory disease, autoimmune disease, and vascular inflammation; and nutrition and therapeutics for these diseases, including the protective abilities of structurally diverse antioxidants, phytochemicals, anti-inflammatory diets, omega-3 fatty acids, nonsteroidal anti-inflammatory drugs (NSAIDS), physical activity, disease modifying anti-rheumatic drugs, and novel regimens.
Historically, medications used to treat PsA have included nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease modifying anti-rheumatic drugs (DMARDs) such as methotrexate, sulfasalazine, and leflunomide.
The European Commission (EC) has granted Regeneron Pharmaceuticals Inc (NASDAQ: REGN) and Sanofi SA (EPA: SAN) marketing authorisation for Kevzara (sarilumab) in combination with methotrexate (MTX) for the treatment of moderately to severely active rheumatoid arthritis (RA) in adult patients who have responded inadequately to, or who are intolerant to, one or more disease modifying anti-rheumatic drugs, the companies announced on Tuesday.

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